Results 101 to 110 of about 978,507 (267)

Adapting Boot Camp Translation Methods to Engage Clinician/Patient Research Teams Within Practice-Based Research Networks: A Report From the INSTTEPP Trial and Meta-LARC Consortium. [PDF]

J Patient Cent Res Rev, 2018
Fagnan LJ, Simpson MJ, Daly JM, Michaels LC, Hahn DL, Levy BT, Fernald DH, Westfall JM, Nease DE.   +8 more
europepmc   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Exploring the role of internship education programmes in fostering students’ entrepreneurship competencies in higher educational institutions

Humanities & Social Sciences Communications
Saudi Arabia’s economic transformation necessitates a skilled entrepreneurial workforce; currently, educational frameworks struggle to develop these capabilities in graduates.
Ali Essa Alshammari, Hamed Mahmoud Shamsaan Ahmed, Murad Ahmed Saleh Thomran, Rayed Obaid Alobaid, Mohieddin Salem Grada, Mustafa Ahmed Al-humari   +5 more
doaj   +1 more source

Health equity: evidence synthesis and knowledge translation methods. [PDF]

Syst Rev, 2013
Welch VA, Petticrew M, O'Neill J, Waters E, Armstrong R, Bhutta ZA, Francis D, Koehlmoos TP, Kristjansson E, Pantoja T, Tugwell P.   +10 more
europepmc   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

Translation methods for english newspaper texts

Russian Language Studies, 2013
The present article is a result of the practical experience in developing translation skills for students of the Law faculty. The article examines the specific stylistic, syntactic, pragmatic and lingo-cultural features of English and Russian newspaper ...
V I Ozyumenko
doaj  

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Promoting Awareness of Key Resources for Evidence-Informed Decision-making in Public Health: An Evaluation of a Webinar Series about Knowledge Translation Methods and Tools. [PDF]

Front Public Health, 2016
Yost J, Mackintosh J, Read K, Dobbins M.
europepmc   +1 more source