Results 131 to 140 of about 1,034,937 (268)

CT-Based Radiostereometric Analysis: A Promising Alternative to Conventional Radiostereometric Analysis in Determining Polyethylene Wear in Total Hip Arthroplasty. [PDF]

Adv Orthop
Kramer E, Sandberg O, Brüggemann A, Hailer NP, Sköldenberg O, Brodén C.   +5 more
europepmc   +1 more source

IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

FEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source

Effect of Dental Chair Backrest Inclination on Mandibular Position Obtained with a Virtual Interocclusal Record at the Maximum Intercuspal Position: A Pilot Clinical Study. [PDF]

Dent J (Basel)
Ali K, Bhumpattarachai S, Savignano R, Possinger M, Kan J.   +4 more
europepmc   +1 more source

Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells

FEBS Open Bio, EarlyView.
Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla, Martín M. Ledesma, Santiago A. Behr, Matías A. Pibuel, María L. Palanek, Daniel H. Grasso, Maria N. Garcia, Juan Garona, Silvina L. Lompardía, Elida Álvarez, Daniela L. Papademetrio   +10 more
wiley   +1 more source

Leveraging local knowledge for crisis management: a practice-based approach to managing uncertainty in healthcare during COVID-19. [PDF]

BMJ Lead
Dionne KE, Malas K, Manent M, Reeves S.
europepmc   +1 more source

Impact of the Diversity in the 5' UTR on Translation Regulation. [PDF]

Wiley Interdiscip Rev RNA
Cardamone G, Flohr M, Bode I, Schmid T.
europepmc   +1 more source

Understanding and Mitigating the Risk of Accelerated Biological Aging in Survivors of Cancer: A Scoping Review

Aging and Cancer, EarlyView.
Cancer treatment is associated with measurable acceleration of biological aging across epigenetic, telomere, senescence, and immune biomarkers. However, biomarker validation and interventional strategies remain limited, especially in hematologic malignancies, underscoring the need for standardized multi‐omic aging assessments and adequately powered ...
Moataz Ellithi, Emily Herdman, Danielle Westmark, Vijaya R. Bhatt   +3 more
wiley   +1 more source

Knowledge Mapping of Human Genetic Variation in Multiomics Biomarker Translation: A Bibliometric Analysis. [PDF]

Hum Mutat
Zhao B, Ran W, Liang N.
europepmc   +1 more source

Self‐Regulated Learning Meets AI: Reinterpreting Self‐Regulation, Co‐Regulation, and Socially Shared Regulation in Human–AI Interaction

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Advancing artificial intelligence (AI) has transformed learning and work, yet higher education and professional development programs have not systematically equipped learners for AI‐prevalent environments. This lack of preparation creates uncertainty regarding control, responsibility, trust, and accountability.
Moon‐Heum Cho, Jerusalem Merkebu
wiley   +1 more source

The development of a technologic approach to improve access to individualized clinical documentation in caregivers' preferred language. [PDF]

PLOS Digit Health
Toscano J, Kwok KY, Simione M.
europepmc   +1 more source