Results 51 to 60 of about 1,301,586 (284)

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Hypercyclic Behavior of Translation Operators on Spaces of Analytic Functions on Hilbert Spaces

Journal of Function Spaces, 2015
We consider special Hilbert spaces of analytic functions of many infinite variables and examine composition operators on these spaces.
Zoryana Mozhyrovska, Andriy V. Zagorodnyuk   +1 more
doaj   +1 more source

The translation operator. Applications to nonlinear reconstruction operators on nonuniform grids

Mathematics and Computers in Simulation, 2023
In this paper, we define a translation operator in a general form to allow for the application of the weighted harmonic mean in different applications. We outline the main steps to follow to define adapted methods using this tool. We give a practical example by improving the behavior of a nonlinear reconstruction operator defined in nonuniform grids ...
Amat Plata, Sergio, Ortiz, Pedro, Ruiz Álvarez, Juan, Trillo Moya, Juan Carlos, Yáñez Avendaño, Dionisio Félix   +4 more
openaire   +3 more sources

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

ON THE STRUCTURE OF 𝐷_𝑊 -APPELL DUNKL CLASSICAL ORTHOGONAL POLYNOMIALS

Проблемы анализа
In this paper, we investigate a class of classical orthogonal polynomials associated with the 𝐷_𝑤-Dunkl operator. This class is defined via a lowering operator that combines the discrete translation operator with a reflection-invariant component.
J. Souissi, K. A. Alanezy
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Spectrum Decomposition of Translation Operators in Periodic Waveguide [PDF]

SIAM Journal on Applied Mathematics, 2021
Scattering problems in periodic waveguides are interesting but also challenging topics in mathematics, both theoretically and numerically. Due to the existence of eigenvalues, the unique solvability of these problems is not always guaranteed. To obtain a unique solution that is "physically meaningful", the limiting absorption principle (LAP) is a ...
openaire   +5 more sources

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Extended BMS algebra of celestial CFT

Journal of High Energy Physics, 2020
We elaborate on the proposal of flat holography in which four-dimensional physics is encoded in two-dimensional celestial conformal field theory (CCFT). The symmetry underlying CCFT is the extended BMS symmetry of (asymptotically) flat space­ time.
Angelos Fotopoulos, Stephan Stieberger, Tomasz R. Taylor, Bin Zhu   +3 more
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source