Delivery of DNA‐encoded vaccines and proteins in mice using cutaneous suction‐mediated transfection
Cutaneous suction‐mediated transfection in mice for delivery of DNA‐encoded vaccines and proteins. A critical limitation of DNA vaccines and other therapeutics is transfection in vivo to produce the encoded antigens or therapeutic proteins. Cutaneous suction‐based methods have demonstrated effectiveness in many animal models and have been successfully ...
Emran O. Lallow +12 more
wiley +1 more source
Finite translation planes having a collineation group isomorphic to SL(2,5) occur in many investigations on minimal normal non-solvable subgroups of linear translation complements. In this paper, we are looking for multiply derived translation planes of
T. Szonyi +5 more
core
Optimizing the correlation between first metatarsal head position and osteotomy plane angle in modified scarf osteotomy: a three-dimensional digital analysis. [PDF]
Yu QW +10 more
europepmc +1 more source
Aging Is a Key Driver for Adult Acute Myeloid Leukemia
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley +1 more source
Rotational Subluxation Patterns on Stress Radiography and Clinical Relevance in PCL-Deficient Knees: A 2D-3D Registration Study. [PDF]
Yang Y +5 more
europepmc +1 more source
Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source
Optimization of Exoskeleton Assistance Function Based on Physics-Guided Dynamic Fusion Model. [PDF]
Tian H, Wang J, Guo S, Cao F, Liu L.
europepmc +1 more source
ABSTRACT Objective To delineate specific in vivo white matter pathology in neuronal intranuclear inclusion disease (NIID) using diffusion spectrum imaging (DSI) and define its clinical relevance. Methods DSI was performed on 42 NIID patients and 38 matched controls.
Kaiyan Jiang +10 more
wiley +1 more source
Translation planes admitting a linear abelian group of order (q+1)²
Translation planes of order q2 and spread in P G(3, q), where q is an odd prime power and q 2 − 1 has a p-primitive divisor, that admit a linear Abelian group of order (q + 1)2 containing at most three kernel homologies are shown to be associated to ...
Diaz, Esteban, Vega, Oscar
core +1 more source
Impact of Asymptomatic Intracranial Hemorrhage on Outcome After Endovascular Stroke Treatment
ABSTRACT Background Endovascular treatment (EVT) achieves high rates of recanalization in acute large‐vessel occlusion (LVO) stroke, but functional recovery remains heterogeneous. While symptomatic intracranial hemorrhage (sICH) has been well studied, the prognostic impact of asymptomatic intracranial hemorrhage (aICH) after EVT is less certain ...
Shihai Yang +22 more
wiley +1 more source

