Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Literacy, translation, practices [PDF]
This article presents a case study about groundwater detection in a mountainous area of South Kordofan in Sudan. The inhabitants of these areas regularly experience water scarcity during dry seasons. Several factors have intensified this scarcity recently, among them protracted civil wars (1987‑2002, 2011-?) and a steady decrease of rainfall. The study
openaire +2 more sources
From LTL and Limit-Deterministic B\"uchi Automata to Deterministic Parity Automata
Controller synthesis for general linear temporal logic (LTL) objectives is a challenging task. The standard approach involves translating the LTL objective into a deterministic parity automaton (DPA) by means of the Safra-Piterman construction.
A Duret-Lutz +12 more
core +1 more source
Effect of finite computational domain on turbulence scaling law in both physical and spectral spaces [PDF]
The well-known translation between the power law of the energy spectrum and that of the correlation function or the second order structure function has been widely used in analyzing random data.
Chen, Shiyi +3 more
core +1 more source
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Integrating Translation Technology in the Specialised Translation Classroom to Contextualise Learning [PDF]
Recent approaches to translation training have emphasized the need to include in the classroom a real working context and to promote situational learning (cf. Kelly, 2005: 16-18 ).
Plaza-Lara, Cristina
core
The Contribution of Conceptual Frameworks to Knowledge Translation Interventions in Physical Therapy [PDF]
Context: There is growing recognition of the importance of knowledge translation activities in physical therapy to ensure that research findings are integrated in clinical practice, and increasing numbers of knowledge translation interventions are ...
Gervais, Mathieu-Joël +2 more
core +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Fostering environmental consciousness among university students [PDF]
During a time marked by environmental issues, it is crucial to educate and empower a generation of knowledgeable individuals. This abstract suggests an all-encompassing method for environmental education designed specifically for university students. The
Mkhitaryan Irina, Sargsyan Lusine
doaj +1 more source
Gap between theory and practice: noise sensitive word alignment in machine translation [PDF]
Word alignment is to estimate a lexical translation probability p(e|f), or to estimate the correspondence g(e, f) where a function g outputs either 0 or 1, between a source word f and a target word e for given bilingual sentences.
Graham, Yvette +2 more
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