Results 161 to 170 of about 2,376,532 (294)

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

The m⁶A reader SlYTH2 negatively regulates tomato fruit aroma by impeding the translation process. [PDF]

Proc Natl Acad Sci U S A
Bian H, Song P, Gao Y, Deng Z, Huang C, Yu L, Wang H, Ye B, Cai Z, Pan Y, Wang F, Liu J, Gao X, Chen K, Jia G, Klee HJ, Zhang B.   +16 more
europepmc   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Premarket Approval Through the 510(k) Process: Lessons from the Translation Process of Magnetic Resonance Elastography. [PDF]

Clin Transl Sci, 2018
Aponte Ortiz JA, Konik E, Eckert EC, Pepin KM, Greenberg-Worisek A.   +4 more
europepmc   +1 more source

Translation as a process

, 2020
Concebidos tradicionalmente em torno de dicotomias bem estabelecidas, os estudos sobre tradução acabam por deixar ainda amplo espaço à construção de um caminho teórico que trate a tradução enquanto processo, não apenas como elemento implícito à existência do produto, mas com uma proposta de conceitos dotados de valor operacional.
openaire   +1 more source

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

FEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar, Francesco Michelangeli, Farhat Latif Khanim, Christopher Martin Bunce, William Eustace Basil Johnson   +4 more
wiley   +1 more source

Translation process of the tested Rome IV diagnostic questionnaire for functional gastrointestinal disorders into Saudi-Arabian Arabic: A mixed-methods approach. [PDF]

Pak J Med Sci
Aljaaly EA, Khatib MA.
europepmc   +1 more source

Patient-Reported Outcome (PRO) Consortium translation process: consensus development of updated best practices. [PDF]

J Patient Rep Outcomes, 2017
Eremenco S, Pease S, Mann S, Berry P, PRO Consortium’s Process Subcommittee.   +4 more
europepmc   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

A Spanish-Language Risk Perception Survey for Developing Diabetes: Translation Process and Assessment of Psychometric Properties. [PDF]

J Nurs Meas, 2016
Joiner KL, Sternberg RM, Kennedy C, Chen JL, Fukuoka Y, Janson SL.   +5 more
europepmc   +1 more source