Results 81 to 90 of about 127,804 (219)

Pirin Transcriptionally Regulates PLA2G4A To Inhibit Ferroptosis in Colorectal Cancer via Lipid Profile Remodeling

open access: yesAdvanced Science, EarlyView.
This study identifies Pirin (PIR), an iron‐binding protein, as a critical ferroptosis suppressor in colorectal cancer through lipid membrane remodeling. PIR, induced by NRF2 during ferroptotic stress, transcriptionally regulates PLA2G4A to shift cellular lipid composition away from ferroptosis‐permissive polyunsaturated phospholipids.
Wei Shi   +10 more
wiley   +1 more source

Proceedings of the 23rd Paediatric Rheumatology European Society Congress: part three

open access: yesPediatric Rheumatology Online Journal, 2017
Riccardo Papa   +782 more
doaj   +1 more source

MAINTAINING FIRST LANGUAGE: BILINGUALS’ VOICES [PDF]

open access: yes, 2014
Indonesia is known as a multicultural country which has thousand different languages Most of its citizens are believed to be able to communicate by using two or morelanguages. This qualitative research, by employing case study approach, was done withthe
Abrar, Mukhlash
core  

Iron Oxide Nanozyme as Reactive Oxygen and Nitrogen Species Scavenger to Regulate Microglial Homeostasis in Stroke

open access: yesAdvanced Science, EarlyView.
6 nm iron oxide nanoparticles (IONP6) exhibit enzyme‐like activities that scavenge reactive oxygen and nitrogen species (RONS), including nitric oxide (NO). In stroke models, IONP6 promotes microglial polarization toward the M2 phenotype, reduces neuroinflammation, and improves neurological outcomes, offering a promising drug‐free approach to mitigate ...
Yilin Qi   +12 more
wiley   +1 more source

Introduction [PDF]

open access: yes, 2012
Traces the history of Bell's Dictionary and Digest from its first author through its subsequent editors, placing the only dictionary of Scots law in its wider international ...
Anderson, R.G.
core  

Arginine Methylation Antagonizes TEAD3‐Mediated Repression to Promote Osteogenic Differentiation by Disrupting RUNX2‐Sequestrating Condensates

open access: yesAdvanced Science, EarlyView.
In the unmethylated state, TEAD forms stable, repressive condensates that sequester the osteogenic master regulator RUNX2. Arginine methylation of TEAD at R55 acts as a molecular brake, dissolving these condensates to release RUNX2 and activate the osteogenic program.
Lei Cao   +6 more
wiley   +1 more source

The development of translation theories in Europe [PDF]

open access: yes, 2012
Este artigo trata do desenvolvimento dos estudos da tradução na Europa, no siculo XX. O maior enfoque está na mudança da perspeciiva de pesquisa, da comparação entre línguas para a confrontação de textos e da focalização datradução como atividade ...
Stolze, Radegundis
core  

A DNA Tetrahedron Delivery Asiatic Acid to Reprogram Mitochondrial Metabolism for Promoting Bone Regeneration via STAT3 Phosphorylation

open access: yesAdvanced Science, EarlyView.
A hyaluronic acid methacrylate (HAMA) hydrogel incorporating DNA tetrahedrons loaded with Asiatic acid (TDN@AA) was developed. HM‐TDN@AA promotes angiogenesis of endothelial cells (ECs), inhibits osteoclastogenesis from bone marrow–derived macrophages (BMDMs), and enhances osteogenesis of mesenchymal stem cells (MSCs) via STAT3‐mediated mitochondrial ...
Yiwen Huang   +9 more
wiley   +1 more source

COMPOUNDING OF BASEMAH LANGUAGE: An Effort to Understand the Uniqueness of Local Languages [PDF]

open access: yes, 2017
The objectives of this research are to describe the compound and identify its kinds in Basemah language. Compound is words formed by combining roots, and the much smaller category of phrasal words, that is items that have internal structure of phrases ...
Mahdi, Sutiono
core  

Precision‐Engineered Silver Single‐Atom Carbon Dot Nanozymes for Theranostic Management of Acute Kidney Injury

open access: yesAdvanced Science, EarlyView.
Mitochondria‐targeted silver single‐atom carbon dot (T‐AgSA‐CDs) nanozymes enable dual SOD/GPx‐like ROS scavenging, real‐time imaging, and therapeutic effects for acute kidney injury (AKI). Atomically dispersed Ag sites synergize with carbon dots to restore renal redox hemostasis, protect mitochondrial function, mitigate inflammation, facilitate post ...
Tianle Tang   +10 more
wiley   +1 more source

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