Results 231 to 240 of about 1,824,000 (291)

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

Advanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio, B. Spedicato, G. Corallo, A. Inguscio, M. Greco, D. Musarò, D. Vergara, A. F. Muro, G. De Sabbata, L. R. Soria, N. Brunetti Pierri, M. Maffia   +11 more
wiley   +1 more source

Tumor organoids in immunotherapy: from disease modeling to translational research. [PDF]

J Immunother Cancer
Si Q, Tao S, Wu J, Ma J, Li Z, Feng X, Song J, Kong T, Zhou Z.   +8 more
europepmc   +1 more source

Air‐Pressure–Actuated Vibroacoustic Metamaterial With Tunable Bandgap: Design, Modeling, and Characterization

Advanced Engineering Materials, EarlyView.
This article presents the design, modeling, and characterization of air‐pressure–actuated programmable vibroacoustic metamaterials (PVAMM). The study focuses on leveraging air pressure to dynamically tune resonance frequencies for effective noise attenuation.
William Kaal, Michael M. Becker, Sarah C. L. Fischer   +2 more
wiley   +1 more source

Proximity Ligation Assay: From a Foundational Principle to a Versatile Platform for Molecular and Translational Research. [PDF]

Biomolecules
Li H, Ma X, Shi D, Wang P.
europepmc   +1 more source

Comment on: Fibrinogen Changes Before and After Intravenous Thrombolysis as Predictors of Cerebral Injury and Clinical Outcomes in Acute Ischemic Stroke—The 24‐h Time‐Point May be a Pro‐Thrombotic Blind Spot: Check 6‐h Fibrinogen Rebound to Catch Early Re‐Occluders

Annals of Clinical and Translational Neurology, EarlyView.
Qichao Fang, Luting Ying, Yongjin Gong
wiley   +1 more source

Engineered Mycelial Scaffolds With Tunable Ultraviolet Protection, Wettability, Thermal Stability, and Spatial Mechanics

Advanced Engineering Materials, EarlyView.
Fungal mycelia grown into biodegradable scaffolds and infused with titania nanoparticles show enhanced ultraviolet shielding, thermal protection, and surface nonwettability. Properties were tuned by drying methods, revealing structure–function relationships.
Juwon S. Afolayan, Xin Zhang, Carole C. Perry   +2 more
wiley   +1 more source

Longitudinal Synthetic Data Generation by Artificial Intelligence to Accelerate Clinical and Translational Research in Breast Cancer. [PDF]

JCO Clin Cancer Inform
Zazzetti E, D'Amico S, Jacobs F, De Sanctis R, Chiudinelli L, Gaudio M, Asti G, Delleani M, Sauta E, Quintavalla M, Bruseghini A, Lanino L, Maggioni G, Campagna A, Savevski V, Della Porta MG, Zambelli A.   +16 more
europepmc   +1 more source

[Translational research].

Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 2003
openaire   +1 more source

3D (Bio) Printing Combined Fiber Fabrication Methods for Tissue Engineering Applications: Possibilities and Limitations

Advanced Functional Materials, EarlyView.
Biofabrication aims at providing innovative technologies and tools for the fabrication of tissue‐like constructs for tissue engineering and regenerative medicine applications. By integrating multiple biofabrication technologies, such as 3D (bio) printing with fiber fabrication methods, it would be more realistic to reconstruct native tissue's ...
Waseem Kitana, Indra Apsite, Leonid Ionov   +2 more
wiley   +1 more source