Results 181 to 190 of about 619,448 (301)

Reducing translational science roadblocks to disability research. [PDF]

J Clin Transl Sci
Bonuck K, Fishman A.
europepmc   +1 more source

Science AMA Series: I'm Ali Torkamani of the Scripps Translational Science Institute and co-leader of the first large scale genomic study of healthy aging. AMA!

, 2016
ScrippsSTSI, r Science
openalex   +1 more source

Mapping the translational science policy ‘valley of death’ [PDF]

, 2013
Eric M. Meslin, Alessandro Blasimme, Anne Cambon‐Thomsen   +2 more
openalex   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

Statins for the "SMuRFLess But Inflamed": Silent Vascular Inflammation and the Challenge of Translational Science. [PDF]

JACC Basic Transl Sci
Ridker PM.
europepmc   +1 more source

The Translational Science as Novel Physiotherapy

, 2012
Thiago Gomes Heck
openalex   +1 more source

The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential

Aging and Cancer, EarlyView.
As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley   +1 more source

TRANSLATIONAL SCIENCE IN CHRONIC TENDINOPATHIES

, 2020
Vijay J Patel, Manish Khanna
openalex   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Using the translational science benefits model to evaluate the impact of community-engaged programs. [PDF]

J Clin Transl Sci
Gomes SM, Murphy BN, Mitchell MJ, Grant A, Jacquez FM, Rosen BL, Crosby LE.   +6 more
europepmc   +1 more source