Results 191 to 200 of about 619,448 (301)

Tracking Motor Progression and Device‐Aided Therapy Eligibility in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterise the progression of motor symptoms and identify eligibility for device‐aided therapies in Parkinson's disease, using both the 5‐2‐1 criteria and a refined clinical definition, while examining differences across genetic subgroups.
David Ledingham, Sahana Sathyanarayana, Charlotte B. Stewart, Robyn Iredale, Victoria Foster, Debra Galley, Mark Baker, Nicola Pavese   +7 more
wiley   +1 more source

Harnessing ovarian cancer ascites for translational science: models, biomarkers, and therapeutics. [PDF]

Mol Cancer
Dogra S, Adhikari L, Benbrook DM, Bohn JA, Burgett A, Chandra V, Dockery L, Singh A, McNally L, Rai R, Isingizwe ZR, Richardson DL, Yang Z, Hannafon BN.   +13 more
europepmc   +1 more source

Accelerated Progression of Gait Impairment in Parkinson's Disease and REM Sleep Without Atonia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective People with Parkinson's disease (PD) and rapid eye movement (REM) sleep without atonia (RSWA) often have more severe gait disturbances compared to PD without RSWA. The association between the presence and expression of RSWA and the rate of progression of gait impairment in PD is unknown.
Sommer L. Amundsen‐Huffmaster, Jae Woo Chung, Maria E. Linn‐Evans, Matthew N. Petrucci, Chiahao Lu, Destiny J. Weaver, Joshua De Kam, Scott E. Cooper, Paul J. Tuite, Aleksandar Videnovic, Michael J. Howell, Colum D. MacKinnon   +11 more
wiley   +1 more source

Researchers' roadblocks to including people with intellectual and developmental disabilities (DD) in research: Translational science and I/DD program leaders insights. [PDF]

J Clin Transl Sci
Bonuck K, George P, Harniss M, Meeuwis F, Iadarola S.   +4 more
europepmc   +1 more source

Doctoral Programs to Train Future Leaders in Clinical and Translational Science

, 2013
Galen E. Switzer, Georgeanna F. W. B. Robinson, Doris M. Rubio, Nicole R. Fowler, Wishwa N. Kapoor   +4 more
openalex   +2 more sources

Diffusion Tractography Biomarker for Epilepsy Severity in Children With Drug‐Resistant Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To develop a novel deep‐learning model of clinical DWI tractography that can accurately predict the general assessment of epilepsy severity (GASE) in pediatric drug‐resistant epilepsy (DRE) and test if it can screen diverse neurocognitive impairments identified through neuropsychological assessments.
Jeong‐Won Jeong, Min‐Hee Lee, Hiroshi Uda, Yoon Ho Hwang, Michael Behen, Aimee Luat, Csaba Juhász, Eishi Asano   +7 more
wiley   +1 more source

Advancing translational science through trial integrity: REDCap-based approaches to mitigating fraud and bias. [PDF]

J Clin Transl Sci
Fronk GE, Hawk LW, Cates A, Clark J, Natale N, Dahne J.   +5 more
europepmc   +1 more source

Table 1_Public health emergency accelerated research response—the Clinical and Translational Science Institute of Southeast Wisconsin COVID-19 research initiative.docx

Michael P. Anello (21287960), Doriel D. Ward (21287963), Orsolya M. Garrison (21287966), Amit Gode (21287969), Octavian C. Ioachimescu (8384508), David R. Friedland (21287972), Reza Shaker (21287975)   +6 more
openalex   +1 more source

113 Creation of an undergraduate certificate program in clinical and translational science following a six-step curriculum development process [PDF]

Jacqueline M. Knapke, Michelle Marcum, Angela Mendell, Patrick Ryan   +3 more
openalex   +1 more source

Decreased Serum 5‐HT: Clinical Correlates and Regulatory Role in NMJ of MG

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Although 5‐Hydroxytryptamine (5‐HT) indirectly stimulates muscle contraction and participates in regulating Acetylcholine receptor (AChR) cluster homeostasis in cellular, animal, and clinical studies, evidence regarding its potential to modulate muscle contraction in myasthenia gravis (MG) remains limited.
Xinru Shen, Jing Zhang, Xinyue Zhou, Xiaoxiao Yu, Haodong Shang, Shufan Chen, Lulu Zhen, Jinru Wu, Guanlian Hu, Xiaoyan Zhu, Zhan Sun, Yiren Wang, Jiahui Wang, Jie Lv, Xue Zhao, Yingna Zhang, Wei Guo, Ying Peng, Feng Gao   +18 more
wiley   +1 more source