Results 51 to 60 of about 764,433 (294)

Limit theorems for skew translations

, 2014
Bufetov, Bufetov-Forni and Bufetov-Solomyak have recently proved limit theorems for translation flows, horocycle flows and tiling flows, respectively.
Griffin, Jory, Marklof, Jens
core   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Structural Refinement for the Modal nu-Calculus [PDF]

, 2014
We introduce a new notion of structural refinement, a sound abstraction of logical implication, for the modal nu-calculus. Using new translations between the modal nu-calculus and disjunctive modal transition systems, we show that these two specification
A.N. Prior, D. Gebler, E.M. Clarke, G. Boudol, J.-B. Raclet, J.B. Hart, K.G. Larsen, K.G. Larsen, K.G. Larsen, K.G. Larsen, L. Alfaro de, L. Alfaro de, M. Hennessy, N. Beneš, N. Beneš, N. Beneš, P. Blackburn, P.W. O’Hearn, S.S. Bauer, S.S. Bauer, S.S. Bauer   +20 more
core   +4 more sources

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Greek-Arabic-Latin: The transmission of mathematical texts in the Middle Ages [PDF]

, 2001
During the Middle Ages many Greek mathematical and astronomical texts were translated from Greek into Arabic (ca. ninth century) and from Arabic into Latin (ca. twelfth century). There were many factors complicating the study of them, such as translation
Lorch, Richard
core   +1 more source

Limitless translation limits translation [PDF]

Nature, 2017
Evidence has now been found that ribosomes — the cell’s translational apparatus — can pass beyond the main protein-coding region of messenger RNAs to form ‘traffic jams’ that inhibit protein expression. Evidence has now been found that ribosomes — the cell’s translational apparatus — can pass beyond the main protein-coding region of messenger RNAs to ...
openaire   +2 more sources

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Telemedicine as a special case of Machine Translation

, 2015
Machine translation is evolving quite rapidly in terms of quality. Nowadays, we have several machine translation systems available in the web, which provide reasonable translations.
Glinkowski, Wojciech, Marasek, Krzysztof, Wołk, Krzysztof   +2 more
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source