Results 51 to 60 of about 663,083 (245)
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
, 2017 The Parallel Meaning Bank is a corpus of translations annotated with shared, formal meaning representations comprising over 11 million words divided over four languages (English, German, Italian, and Dutch).
Abzianidze, Lasha +7 more
core +1 more source
Limitless translation limits translation [PDF]
Nature, 2017 Evidence has now been found that ribosomes — the cell’s translational apparatus — can pass beyond the main protein-coding region of messenger RNAs to form ‘traffic jams’ that inhibit protein expression. Evidence has now been found that ribosomes — the cell’s translational apparatus — can pass beyond the main protein-coding region of messenger RNAs to ...
openaire +2 more sources
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Adequacy of compositional translations for observational semantics [PDF]
, 2008 We investigate methods and tools for analysing translations between programming languages with respect to observational semantics. The behaviour of programs is observed in terms of may- and must-convergence in arbitrary contexts, and adequacy of ...
Niehren, Joachim +3 more
core +8 more sources
, 2016 Quantified Boolean formulas (QBFs) generalize propositional formulas by admitting quantifications over propositional variables. QBFs can be viewed as (restricted) formulas of first-order predicate logic and easy translations of QBFs into first-order ...
Egly, Uwe
core +2 more sources
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Serialised Translations in the Estonian Newspapers in the Beginning of the 20th Century (1900‒1940)
KnygotyraThe paper explores the serialised novels and stories in the two leading Estonian daily newspapers, Päewaleht and Postimees, the majority of which were translations.
Aile Möldre
doaj +3 more sources
Modular Groups of Quantum Fields in Thermal States
, 1998 For a quantum field in a thermal equilibrium state we discuss the group generated by time translations and the modular action associated with an algebra invariant under half-sided translations.
Borchers H.-J. +3 more
core +1 more source
Portugal y España: el siglo 'Pessoa' [PDF]
Pessoa Plural, 2019 La recepción de la obra de Fernando Pessoa en España consta de tres fases: una primera, correspondiente al periodo de vida del escritor, en la que aparecen la primera traducción en español y los contactos con algunos autores castellanos; una segunda ...
Sáez Delgado, Antonio
doaj +1 more source