Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth +6 more
wiley +1 more source
Personalized translator training in the era of digital intelligence: Opportunities, challenges, and prospects. [PDF]
Tian X.
europepmc +1 more source
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda +12 more
wiley +1 more source
Barriers to seeking healthcare services and contributing factors to grade 2 disability among women affected by leprosy in Telangana, India - a qualitative study. [PDF]
Nehring C +6 more
europepmc +1 more source
This study underscores the significant influence of frailty and vitality on the subjective health experience of older cancer survivors with acceptance and control emerging as salient mediators. These findings affirm the conceptual and empirical robustness of the model highlighting its potential utility in shaping future interventions for older cancer ...
Damien S. E. Broekharst +4 more
wiley +1 more source
Testing a novel theoretical framework to study language services implementation in health care. [PDF]
Squires A +4 more
europepmc +1 more source
Kathaper gar tis mètèr... Two Slavonic Translations of Chapters 25-27 of Gregory of Nyssa's De hominis opificio [PDF]
Sels, Lara
core +1 more source
The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential
As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley +1 more source
Comparing ChatGPT-4 and Human Translation of an Outcome Questionnaire: A Randomized, Double-Blinded Non-inferiority Study. [PDF]
Sørensen CB +3 more
europepmc +1 more source

