Results 171 to 180 of about 451,700 (244)

Corn Zein Nanocarriers for Agrochemical Delivery and Smart Packaging

open access: yesAdvanced Sustainable Systems, EarlyView.
This review explores zein, a corn‐derived biodegradable protein, as a multifunctional nanocarrier for sustainable agriculture and packaging. It examines advances in agrochemical delivery, smart packaging, and stimuli‐responsive systems, while addressing scalability, environmental fate, and regulatory barriers.
Muhammad Shahidul Islam   +2 more
wiley   +1 more source

MYC Point Mutations in Cancer: A Reboot and a Sequel. [PDF]

open access: yesClin Cancer Res
De Luca D   +3 more
europepmc   +1 more source

Substrate‐Restricted Asymmetric Evolution of Solid‐State Nanopores

open access: yesAdvanced Theory and Simulations, EarlyView.
Standalone nanopores can either expand or shrink based on the nucleation mechanism. A substrate‐restricted asymmetric pore dynamics are uncovered ‐ top expansion and bottom shrinkage, with minimum aperture reduced and forming a conical geometry, driven by molecular migration along an energy potential gradient within nanopores.
Hongshuai Liu   +4 more
wiley   +1 more source

Excessive DNA Double‐Strand Breaks–Associated 3D Genome Reorganization Contributes to Neural Tube Defects with Folate Deficiency

open access: yesAdvanced Science, EarlyView.
Neural tube defects (NTDs) are among the most common congenital malformations. However, the underlying etiology and mechanism remain elusive. Here, the role of DNA double‐strand breaks (DSBs) in 3D genome organization within the NTDs with folate deficiency is reported.
Ting Zhang   +12 more
wiley   +1 more source

Balanced Translocations Involving the <i>DMD</i> Gene as a Cause of Muscular Dystrophy in Female Children: A Description of Three Cases. [PDF]

open access: yesInt J Mol Sci
Vorontsova EO   +18 more
europepmc   +1 more source

UCP2 Upregulates ACSL3 to Enhance Lipid Droplet Release from Acinar Cells and Modulates the Sirt1/Smad3 Pathway to Promote Macrophage‐to‐Myofibroblast Transition in Chronic Pancreatitis

open access: yesAdvanced Science, EarlyView.
These findings suggest that UCP2 promotes LD formation and release in acinar cells by upregulating ACSL3 expression. This alteration in the local lipid metabolic environment indirectly drives the MMT process. Additionally, UCP2 may regulate the acetylation of Smad3 through Sirt1, enhancing its nuclear activity and activating the TGF‐β/ Smad3 signaling ...
Kunpeng Wang   +9 more
wiley   +1 more source

Genetic rescue of Florida panthers reduced homozygosity but did not swamp ancestral genotypes. [PDF]

open access: yesProc Natl Acad Sci U S A
Aguilar-Gómez D   +8 more
europepmc   +1 more source

Exploring Functionally Enhanced BLP‐Trained Macrophage Subpopulations in S. Aureus Infection: Underlying Mechanisms and Therapeutic Significance

open access: yesAdvanced Science, EarlyView.
BLP‐trained macrophages show augmented resistance to infection, but their mechanisms remain unclear. scRNA‐seq identified 13 BMDM subsets, with two novel anti‐inflammatory/antibacterial subpopulations (C5/C7) emerging post‐BLP training. BLP training activates NRF2, attenuates oxidative stress/ferroptosis, and boosts glycolysis/OXPHOS. Adoptive transfer
Yantong Wan   +13 more
wiley   +1 more source

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