Results 211 to 220 of about 3,184,218 (349)

Genomic features of the Helicobacter pylori strain PMSS1 and its virulence attributes as deduced from its in vivo colonisation patterns

, 2018
Brinkmann, V., Brüggemann, H., Dyer, V., Hoffman, K., Koch, M., Kühl, A., Meyer, T., Reines, M., Soerensen, M., Zimmerman, S.   +9 more
core   +1 more source

Genetic selection for protein solubility enabled by the folding quality control feature of the twin‐arginine translocation pathway

Protein Science, 2006
Adam C. Fisher, W. Kim, M. DeLisa
semanticscholar   +1 more source

piR‐RCC Suppresses Renal Cell Carcinoma Progression by Facilitating YBX‐1 Cytoplasm Localization

Advanced Science, EarlyView.
PIWI‐interacting RNAs (piRNAs), a novel category of small non‐coding RNAs, have been implicated in the development of various diseases. This study explores the tumor‐suppressive mechanism of a downregulated piRNA (designated piR‐RCC) in renal cell carcinoma (RCC), and provides a delivery strategy targeting RCC tumor by constructing a cell membrane ...
Ruyue Wang, Fan Li, Yudong Lin, Zeyi Lu, Wenqin Luo, Zhehao Xu, Ziwei Zhu, Yi Lu, Xudong Mao, Yang Li, Zhinian Shen, Haohua Lu, Yining Chen, Liqun Xia, Mingchao Wang, Lifeng Ding, Gonghui Li   +16 more
wiley   +1 more source

Assessment and Mitigation of CRISPR-Cas9-Induced Nontargeted Translocations. [PDF]

Adv Sci (Weinh)
Hou Z, Yi Q, Wu M, Wu L, Li F, Wang T, Bian P.   +6 more
europepmc   +1 more source

A GENETIC STUDY OF SEGREGATION IN A TRANSLOCATION HETEROZYGOTE IN DROSOPHILA [PDF]

Genetics, 1955
openaire   +3 more sources

Neuraminidase 1 Exacerbated Glycolytic Dysregulation and Cardiotoxicity by Destabilizing SIRT1 through Interactions with NRF2 and HIF1α

Advanced Science, EarlyView.
NEU1, a key regulator of glycolysis, is markedly upregulated following DOX treatment. This upregulation is attributed to HIF1α’s transcriptional repression, requiring intricate interactions with NRF2. Increased NEU1 facilitates SIRT1 lysosomal degradation, contributing to aberrant glycolytic phenotype and cardiac damage.
Ting Gao, Yufeng Tang, Tao Zeng, Jie Wang, Xiaohui Zhang, Qingbo Liu, Xun Guan, Xinyu Tang, Guangping Lu, Jiahao Li, Mingrui Liu, Dongmei Zhang, Sixuan Lv, Junlian Gu   +13 more
wiley   +1 more source

Utilization of Antagonistic Interactions Between Micronutrients and Cadmium (Cd) to Alleviate Cd Toxicity and Accumulation in Crops. [PDF]

Plants (Basel)
Shahzad M, Bibi A, Khan A, Shahzad A, Xu Z, Maruza TM, Zhang G.   +6 more
europepmc   +1 more source

PSMD14 Stabilizes SLC7A11 to Ameliorate Glucocorticoid‐Induced Osteoporosis by Suppressing Osteocyte Ferroptosis

Advanced Science, EarlyView.
Glucocorticoid‐induced osteoporosis (GIOP) triggers osteocyte ferroptosis via SLC7A11 degradation. PSMD14 stabilizes SLC7A11 by counteracting glucocorticoid‐driven ubiquitination, preserving cystine uptake and glutathione synthesis. AAV‐mediated PSMD14 delivery or its agonist Pantethine rescues osteocyte survival and bone loss in GIOP mice.
Yifeng Shi, Qian Tang, Sunren Sheng, Hongyi Jiang, Chen Jin, Chencheng Zhou, Chenglong Xie, Lin Zheng, Di Zhang, Hui Xu, Cong Xu, Haiwei Ma, Guangheng Xiang, Wenfei Ni, Xiaoyun Pan, Lei Yang, Huazi Xu, Yu Qian, Aimin Wu, Xiangyang Wang, Gang Zheng   +20 more
wiley   +1 more source

Genetic and Biochemical Analysis of the Twin-Arginine Translocation Pathway in Halophilic Archaea

Journal of Bacteriology, 2005
Kieran Dilks, M. I. Giménez, M. Pohlschröder   +2 more
semanticscholar   +1 more source

Listerin Alleviates Alzheimer's Disease through IRE1‐mediated Decay of TLR4 mRNA

Advanced Science, EarlyView.
Alzheimer's disease (AD) progression is influenced by microglia‐mediated neuroinflammation. Here, it is demonstrated that Listerin suppresses neuroinflammatory signaling and cognitive impairment in AD models by triggering IRE1α‐mediated TLR4 mRNA decay. Adenoviral Listerin delivery reduces amyloid‐β pathology, positioning it as a new therapeutic target.
Fei Qin, Runyu Cao, Xuemei Bai, Jiahua Yuan, Wanwei Sun, Yi Zheng, Xiaopeng Qi, Wei Zhao, Bingyu Liu, Chengjiang Gao   +9 more
wiley   +1 more source