Results 231 to 240 of about 3,184,218 (349)

NF-κB-mediated developmental delay extends lifespan in <i>Drosophila</i>. [PDF]

Proc Natl Acad Sci U S A
Kang P, Liu P, Hu Y, Kim J, Kumar A, Dorneich-Hayes MK, Murzyn W, Anderson ZJ, Frank LN, Kavlock N, Hoffman E, Martin CC, Miao T, Shimell M, Powell-Coffman JA, O'Connor MB, Perrimon N, Bai H.   +17 more
europepmc   +1 more source

AhR‐Dependent Induction of β‐Defensin 1 in Colonic Epithelial Cells Regulates Cross‐Talk between Gut Microbiota and Immune Response Leading to Attenuation of Colitis

Advanced Science, EarlyView.
This study identifies a key signaling pathway involving the environmental sensor AhR and antimicrobial peptides, such as BD‐1, in the regulation of intestinal homeostasis. It highlights the role of BD‐1 in regulating gut microbiota and the intestinal immune response.
Manikandan Palrasu, Amarnath Marudamuthu, Khadija Kakar, Hamida Hamida, Shruthi Thada, Rohan Gupta, Kiesha Wilson, Taylor Carter, Yin Zhong, Archana Saxena, Xiaoming Yang, Narendra Singh, Philip Brandon Busbee, Jie Li, Monica Garcia‐Buitrago, Prakash Nagarkatti, Mitzi Nagarkatti   +16 more
wiley   +1 more source

Defining the Protein Phosphatase 2A (PP2A) Subcomplexes That Regulate FoxO Transcription Factor Localization. [PDF]

Cells
Luperchio AM, Salamango DJ.
europepmc   +1 more source

Cardiomyocyte‐Enriched USP20 Ameliorates Pathological Cardiac Hypertrophy by Targeting STAT3 Deubiquitination

Advanced Science, EarlyView.
Cardiomyocyte‐enriched USP20 regulates the K63‐linked ubiquitination of STAT3, and the cardiomyocyte‐specific USP20‐STAT3‐CARM1 axis exerts a protective role in cardiac hypertrophy. Targeting USP20 through cardiac‐specific gene therapy presents a promising strategy for the treatment of cardiac hypertrophy.
Lingfeng Zhong, Shanshan Dai, Fan Yu, Guo‐Ping Shi, Qinyan Gong, Yucong Zhang, Jingsi Duan, Zhengyin Lou, Zhixuan Tang, Fuzhe Gong, Derong Chen, Liya Hou, Xinyang Hu, Jinghai Chen, Jian'an Wang, Deling Yin   +15 more
wiley   +1 more source

MYC alterations in multiple myeloma: Genetic insights and prognostic impact. [PDF]

Neoplasia
Cristóbal-Vargas S, Cuadrado M, Gutiérrez NC.   +2 more
europepmc   +1 more source

Genetic Behaviour of Induced Translocation Heterozygote in Poppy

CYTOLOGIA, 2012
Sana Naseem, Girjesh Kumar
openaire   +3 more sources

Gelsolin's Protective Role in MASH through F‐Actin Regulation and P53 Degradation

Advanced Science, EarlyView.
Gelsolin (GSN) maintains liver metabolic homeostasis by promoting MDM2‐mediated P53 degradation and inhibiting F‐actin/Yes‐associated protein (YAP) overactivation. Loss of GSN impairs P53 degradation, increases lipid deposition, and enhances YAP‐driven fibrosis and inflammation in metabolic‐associated steatohepatitis.
Yiwei Lu, Tong Ji, Zhichao Ye, Jianing Yan, Chao Wang, Jiachen Chen, Ziyang Jin, Yongji Zhu, Xiujun Cai, Yifan Wang   +9 more
wiley   +1 more source

Identification of candidate host-specificity genes in Exserohilum turcicum using comparative genomics and transcriptomics. [PDF]

G3 (Bethesda)
Krone MJ, Adhikari P, Singh P, Jamann TM, Mideros SX.   +4 more
europepmc   +1 more source

JA‐Mediated Regulation of Amino Acid Homeostasis Adjusts Metabolic Flux and Enhances Spider Mite Tolerance via the SlJAZ8‐SlWRKY57‐SlAVT6s Module in Tomato

Advanced Science, EarlyView.
This study elucidates a novel SlJAZ8‐SlWRKY57‐SlAVT6A/SlAVT6B module that effectively channels metabolic flux from primary to secondary metabolism, impacting plant growth, development, and resistance. Two novel vacuolar amino acid exporters, SlAVT6A and SlAVT6B, fine‐tunes trichomes, terpenes, and gibberellins, bolstering spider mite resistance.
Yingchen Hao, Xiaolong Wang, Langchen Guo, Lijun Xiang, Enxi Luo, Peng Cao, Penghui Liu, Yue Zhong, Chun Li, Jun Lai, Jun Yang, Shouchuang Wang   +11 more
wiley   +1 more source

Metastatic MiT family/TFE translocation renal cell carcinoma in adults: case series reports and literature reviews. [PDF]

Front Oncol
Sun X, Wang H, Man X, Chen C, Cong X, Zhang J, Yang L.   +6 more
europepmc   +1 more source