Results 21 to 30 of about 3,198,903 (351)
A dual origin for Bcr-Abl gene translocation/fusion as dynamics of synergism of the hematopoietic stem cell and hemangioblast in chronic myeloid leukemia [PDF]
, 2015 Contextual BCR-ABL tyrosine kinase over-activity determines in formulated fashion the emergence of proliferation and anti-apoptosis that arise largely as derived phenomena of otherwise homeostatic mechanisms of the c-ABL gene within hematopoietic ...
Agius, Lawrence M.
core +1 more source
BMC Medical Genomics, 2017 Preimplantation genetic diagnosis (PGD) is now widely used to select embryos free of chromosomal copy number variations (CNV) from chromosome balanced translocation carriers. However, it remains a difficulty to distinguish in embryos between balanced and
Shuo Zhang +9 more
semanticscholar +1 more source
Molecular Cytogenetics, 2018 Background Balanced translocations may cause the loss of genetic material at the breakpoints and may result in failure of spermatogenesis. However, carriers of reciprocal translocation may naturally conceive.
Hong-Guo Zhang +6 more
doaj +1 more source
Bridge-induced chromosome translocation in yeast relies upon a Rad54/Rdh54-dependent, Pol32-independent pathway. [PDF]
PLoS ONE, 2013 While in mammalian cells the genetic determinism of chromosomal translocation remains unclear, the yeast Saccharomyces cerevisiae has become an ideal model system to generate ad hoc translocations and analyze their cellular and molecular outcome.
Valentina Tosato +2 more
doaj +1 more source
PLoS ONE, 2015 Background Established causes of recurrent pregnancy loss (RPL) include antiphospholipid syndrome, uterine anomalies, parental chromosomal abnormalities, particularly translocations, and abnormal embryonic karyotypes.
S. Ikuma +5 more
semanticscholar +1 more source
Cisgenesis, a new tool for traditional plant breeding, should be exempted from the regulation on genetically modified organisms in a step by step approach [PDF]
, 2008 Modern potato breeding requires over 100,000 seedlings per new variety. Main reasons are (1) the increasing number of traits that have to be combined in this tetraploid vegetatively propagated crop, and (2) an increasing number of traits (e.g ...
Jacobsen, E., Schouten, H.J.
core +2 more sources
Computing translocation distance by a genetic algorithm [PDF]
2015 Latin American Computing Conference (CLEI), 2015 Translocation is a useful operation on strings with challenging questions in combinatorics of permutations and interesting applications in analysis of sequences. A translocation operation essentially is the interchange of prefixes and suffixes among two substrings of a string. For the case of genomes represented as strings, symbols that represent genes
Mauricio Ayala-Rincón +3 more
openaire +2 more sources
Genetic mapping of legume orthologs reveals high conservation of synteny between lentil species and the sequenced genomes of Medicago and chickpea. [PDF]
, 2014 Lentil (Lens culinaris Medik.) is a global food crop with increasing importance for food security in south Asia and other regions. Lens ervoides, a wild relative of cultivated lentil, is an important source of agronomic trait variation.
Albert eVandenberg +9 more
core +3 more sources
Major translocations in genetic counselling
Asian Pacific Journal of Reproduction, 2012 Abstract Objective To review major chromosome translocation, with special regard to the clinical differences between balanced and unbalanced, as well as de novo and inherited cases. Methods The authors have included cases of major chromosome translocations detected during a 20-year period.
Ákos Csaba +4 more
openaire +2 more sources
Preimplantation genetic diagnosis for an insertional translocation carrier [PDF]
Human Reproduction, 2004 While preimplantation genetic diagnosis (PGD) is well established for carriers of reciprocal terminal translocations, reports on PGD for insertional translocation carriers are lacking. Here, we report on the PGD of an insertional translocation carrier with karyotype 46,XX,ins(14;2)(q21;q31q35).
Cindy Melotte +4 more
openaire +3 more sources