Results 21 to 30 of about 2,347,193 (305)

Bridge-induced chromosome translocation in yeast relies upon a Rad54/Rdh54-dependent, Pol32-independent pathway. [PDF]

PLoS ONE, 2013
While in mammalian cells the genetic determinism of chromosomal translocation remains unclear, the yeast Saccharomyces cerevisiae has become an ideal model system to generate ad hoc translocations and analyze their cellular and molecular outcome.
Valentina Tosato, Sabrina Sidari, Carlo V Bruschi   +2 more
doaj   +1 more source

Mobility of the SecA 2-helix-finger is not essential for polypeptide translocation via the SecYEG complex [PDF]

, 2012
The bacterial ATPase SecA and protein channel complex SecYEG form the core of an essential protein translocation machinery. The nature of the conformational changes induced by each stage of the hydrolytic cycle of ATP and how they are coupled to protein ...
Allen, William J, Collinson, I, Ian Collinson, Allen, WJ, Vicki A.M. Gold, Alice Robson, Gold, VAM, Whitehouse, Sarah, Gold, Vicki A M, Robson, Alice, Whitehouse, S, Collinson, Ian, Robson, A, William J. Allen, Sessions, RB, Sarah Whitehouse, Sessions, Richard B, Richard B. Sessions   +17 more
core   +1 more source

Preimplantation genetic diagnosis for an insertional translocation carrier [PDF]

Human Reproduction, 2004
While preimplantation genetic diagnosis (PGD) is well established for carriers of reciprocal terminal translocations, reports on PGD for insertional translocation carriers are lacking. Here, we report on the PGD of an insertional translocation carrier with karyotype 46,XX,ins(14;2)(q21;q31q35).
C, Melotte, S, Debrock, T, D'Hooghe, J P, Fryns, J R, Vermeesch   +4 more
openaire   +2 more sources

Structure of a translocation signal domain mediating conjugative transfer by Type IV secretion systems [PDF]

, 2013
Relaxases are proteins responsible for the transfer of plasmid and chromosomal DNA from one bacterium to another during conjugation. They covalently react with a specific phosphodiester bond within DNA origin of transfer sequences, forming a nucleo ...
Redzej, Adam, Topf, Maya, Zechner, E.L., Lang, S., Waksman, Gabriel, Zangger, K., Gruber, C.J., Ilangovan, Aravindan   +7 more
core   +1 more source

Translocation of DNA across bacterial membranes [PDF]

, 1994
Dreiseikelmann B. Translocation of DNA across bacterial membranes. Microbiological Reviews.
Dreiseikelmann, Brigitte
core   +1 more source

Genetic diversity for grain Zn concentration in finger millet genotypes: Potential for improving human Zn nutrition

Crop Journal, 2016
Nearly half of the world population suffers from micronutrient malnutrition, particularly Zn deficiency. It is important to understand genetic variation for uptake and translocation behaviors of Zn in relevant crop species to increase Zn concentration in
Ramegowda Yamunarani , Geetha Govind , Venkategowda Ramegowda , Harshavardhan Vokkaliga Thammegowda , Shankar Ambarahalli Guligowda   +4 more
doaj   +1 more source

Sinonasal FUS-ERG-Rearranged Ewing’s Sarcoma Mimicking Glomangiopericytoma

Case Reports in Oncology, 2020
Ewing’s sarcoma is a rare and aggressive tumor that typically arises in the long bones of the extremities. It belongs in the family of small round blue cell tumors and is characterized immunohistochemically by diffuse CD99 expression and molecularly by ...
Maggie Zhou, Yen Chen Kevin Ko, Gregory W. Charville, Kristen N. Ganjoo   +3 more
doaj   +1 more source

Functional brain defects in a mouse model of a chromosomal t(1;11) translocation that disrupts DISC1 and confers increased risk of psychiatric illness

Translational Psychiatry, 2021
A balanced t(1;11) translocation that directly disrupts DISC1 is linked to schizophrenia and affective disorders. We previously showed that a mutant mouse, named Der1, recapitulates the effect of the translocation upon DISC1 expression.
Marion Bonneau, Shane T. O’ Sullivan, Miguel A. Gonzalez-Lozano, Paul Baxter, Phillippe Gautier, Elena Marchisella, Neil R. Hardingham, Robert A. Chesters, Helen Torrance, David M. Howard, Maurits A. Jansen, Melanie McMillan, Yasmin Singh, Michel Didier, Frank Koopmans, Colin A. Semple, Andrew M. McIntosh, Hansjürgen Volkmer, Maarten Loos, Kevin Fox, Giles E. Hardingham, Anthony C. Vernon, David J. Porteous, August B. Smit, David J. Price, J. Kirsty Millar   +25 more
doaj   +1 more source

Molecular and genetic studies on the region of translocation and duplication in the neuroblastoma cell line NGP at the 1p36.13-p36.32 chromosomal site

, 1996
Cytogenetic and molecular studies suggest that chromosome 1p might contain oncosuppressor genes involved in the pathogenesis of neuroblastoma and other adult tumors. The isolation of these genes by the 'positional cloning' approach will be facilitated by
Opdenakker, G., Romani, M., Volpi, E.V., Marchi, J.V.M., Muresu, R., Rozzo, C., Casciano, I.   +6 more
core   +5 more sources

The decision on the embryo to transfer after Preimplantation Genetic Diagnosis for X-autosome reciprocal translocation in male carrier

Molecular Cytogenetics, 2018
Background The aim of Preimplantation Genetic Diagnosis (PGD) on embryos produced in vitro is to identify the embryos without genetic or chromosomal defect from those embryos that will develop the genetic disease or are chromosomally abnormal. In case of
Sandrine Chamayou, Maria Sicali, Debora Lombardo, Carmelita Alecci, Antonino Guglielmino   +4 more
doaj   +1 more source