Results 291 to 300 of about 3,324,185 (335)

Monitoring and detecting translocations using genetic data

2001
Review on the possiblity to detect and monitor translocation events using genetic data for conservation biology ...
BERTORELLE, Giorgio, PAPETTI C, Hauffe H. C., BOITANI L.   +3 more
openaire   +4 more sources

Translocations as Genetic Markers

1994
If two nonhomologous chromosomes interchange ends following chromosome breakage, the products of this event are termed a reciprocal interchange or reciprocal translocation. The two rearranged chromosomes that result are fully stable and, when transmitted together, contain all the chromosomal material that was present in the two normally arranged ...
openaire   +1 more source

[Robertsonian translocation and genetic counseling].

Journal de genetique humaine, 1988
A collaborative study on 92 Robertsonian translocations is analysed in relation with the methods of ascertainment, the type of rearrangement and potential imbalance of the anomaly. The results are useful in genetic counselling.
L F, Formiga, B, Le Marec, F, Serville, S, Gilgenkrantz   +3 more
openaire   +1 more source

Gross Deletions and Translocations in Human Genetic Disease

2006
Translocations and gross deletions constitute an important cause of both cancer and inherited disease. Such gene rearrangements are non-randomly distributed in the human genome as a consequence of selection for growth advantage and/or the inherent potential of some DNA sequences to be frequently involved in breakage and recombination.
S S, Abeysinghe, N, Chuzhanova, D N, Cooper   +2 more
openaire   +2 more sources

Genetic structure in Elk persists after translocation

The Journal of Wildlife Management, 2018
ABSTRACTElk (Cervus canadensis) translocation success is thought to be facilitated by high post‐release herd cohesion and limited movements; both should ensure genetic mixing following release. Such mixing is important to reduce potential effects of inbreeding or genetic drift, which can be especially important in small founding populations.
Lisa I. Muller, Jennifer L. Murrow, Jason L. Lupardus, Joseph D. Clark, Joseph G. Yarkovich, William H. Stiver, E. Kim Delozier, Brittany L. Slabach, John. J. Cox, Bradley F. Miller   +9 more
openaire   +1 more source

[Preimplantation genetic diagnosis of translocation].

Zhonghua fu chan ke za zhi, 2011
To observe the genetic characteristics of chromosomes and the rates of implantation and pregnancy in couples of translocation carriers who undergo preimplantation genetic diagnosis (PGD) and to evaluate the significance of PGD in the treatment of translocation carriers.Fluorescence in situ hybridization (FISH) was performed to analyze the embryos of 12
Yu-Li, Qian, Chen-Ming, Xu, Fan, Jin, Yi-Min, Zhu, Qiong, Luo, He-Feng, Huang   +5 more
openaire   +1 more source

Preimplantation genetic diagnosis for couples at high risk of Down syndrome pregnancy owing to parental translocation or mosaicism

Journal of Medical Genetics, 1999
The population risk for trisomy 21 is 1 in 700 births but some couples are at a much higher risk owing to parental translocation or mosaicism. We report on the first attempt to carry out preimplantation genetic diagnosis for two such couples using ...
C. M. Conn, J. Cozzi, J. Harper, R. Winston, J. Delhanty   +4 more
semanticscholar   +1 more source

Variant translocations (9;11): Identification of the critical genetic rearrangement

Cancer Genetics and Cytogenetics, 1988
The t(9;11)(p22;q23) is a recurring abnormality in acute nonlymphocytic leukemia. The analysis of complex 9;11 translocations will aid in the identification of the conserved chromosomal junction or the critical genetic alteration created by the rearrangement; however, variant translocations involving chromosomes #9 and #11 have not been reported.
B N, Harris, E M, Davis, M M, Le Beau, M A, Bitter, L S, Kaminer, E, Morgan, J D, Rowley   +6 more
openaire   +2 more sources

[Translocation (X; Y) and genetic counseling].

Journal de genetique humaine, 1988
A t(X; Y) was discovered in 32 year-old female patient who has had three consecutive miscarriages. Molecular analysis of the loci DXS 31 and DYS 22 was performed which confirmed and precise the breakpoints at Xp22.3 and Yq11. Genetic counselling was based upon the accurate definition of the chromosome rearrangement and the analysis of the outcomes of ...
F, Mugneret, I, Sidaner, A, Nivelon-Chevallier, M, Koening, F, Parise, C, Turc-Carel   +5 more
openaire   +1 more source

Translocation-specific polymerase chain reaction in preimplantation genetic testing for recurrent translocation carrier

Journal of Human Genetics
It is occasionally necessary to distinguish balanced reciprocal translocations from normal diploidy since balanced carriers can have reproductive problems or manifest other disease phenotypes. It is challenging to do this however using next generation sequencing (NGS) or microarray-based preimplantation genetic testing (PGT).
Gen Furukawa, Rie Kawamura, Hidehito Inagaki, Yoshihiko Sakakibara, Yoshimasa Asada, Tetsuaki Hara, Takeshi Iwasa, Akira Kuwahara, Minoru Irahara, Hiroki Kurahashi   +9 more
openaire   +2 more sources