The translocation step of elongation entails the coordinated movement of tRNA and mRNA on the ribosome. Translocation is promoted by elongation factor G (EF-G) and accompanied by GTP hydrolysis, which affects both translocation and turnover of EF-G. Both reactions are much slower (50-100-fold) when GTP is replaced with non-hydrolyzable GTP analogues or
Katunin, Vladimir I. +3 more
openaire +5 more sources
Factors Influencing the Postrelease Movements of Translocated Fishers: Implications for Translocation Success [PDF]
Abstract Long-distance, postrelease movements of translocated wildlife can be a key factor limiting translocation success. Yet, for many species, we have little or no understanding of factors that influence postrelease movements. Translocations have been important for recovering fisher Pekania pennanti populations across the southern ...
Jeffrey C. Lewis +3 more
openaire +1 more source
Transcription factors, translocations, and leukemia [PDF]
Abstract The frequent occurrence of TF gene involvement in translocations associated with leukemia is remarkable, although not yet explained. The wide variety of TFs involved in these translocations and the different stages of cellular maturation argue against a unifying mechanism.
J, Nichols, S D, Nimer
openaire +3 more sources
Factors That Affect the Formation of Chromosomal Translocations in Cells
Chromosomal translocations are products of the illegitimate repair of DNA double-strand breaks (DSBs). Their formation can bring about significant structural and molecular changes in the cell that can be physiologically and pathologically relevant. The induced changes may lead to serious and life-threatening diseases such as cancer.
Reynand Jay Canoy +5 more
openaire +2 more sources
Virulence factor secretion and translocation by Bordetella species [PDF]
Here we review the Bordetella virulence secretome with an emphasis on factors that translocate into target cells. Recent advances in understanding the functions of adenylate cyclase toxin, a type 1 secretion system (T1SS) substrate, and pertussis toxin, a type IV secretion system (T4SS) substrate, are briefly described and a compilation of additional ...
Ruchi, Shrivastava, Jeff F, Miller
openaire +2 more sources
Protein translocation across mitochondrial membranes [PDF]
Protein translocation across biological membranes is of fundamental importance for the biogenesis of organelles and in protein secretion. We will give an overview of the recent achievements in the understanding of protein translocation across ...
Walter Neupert +3 more
core +1 more source
Protein folding causes an arrest of preprotein translocation into mitochondria in vivo [PDF]
With vital yeast cells, a hybrid protein consisting of the amino- terminal third of the precursor to cytochrome b2 and of the entire dihydrofolate reductase was arrested on the import pathway into mitochondria.
W Neupert +15 more
core +2 more sources
Growth and Distribution of Boron in Oilseed Rape (Brassica napus L.) as Affected by Boron Supply
Oilseed rape (Brassica napus L.) is one of the most important oilseed crops. It has relatively high boron (B) requirements for growth. In this study, a hydroponic experiment was performed to determine the critical B requirement and B distribution in B ...
Anh Quang Dinh +2 more
doaj +1 more source
Designed Azolopyridinium Salts Block Protective Antigen Pores In Vitro and Protect Cells from Anthrax Toxin [PDF]
Background:Several intracellular acting bacterial protein toxins of the AB-type, which are known to enter cells by endocytosis, are shown to produce channels.
Barth, Holger +24 more
core +2 more sources
Copper Tolerance and Accumulation on Pelargonium graveolens L’Hér. Grown in Hydroponic Culture
Heavy metal contamination is a major health issue concerning the commercial production of medicinal and aromatic plants (MAPs) that are used for the extraction of bioactive molecules. Copper (Cu) is an anthropogenic contaminant that, at toxic levels, can
Antonios Chrysargyris +4 more
doaj +1 more source

