NR4A1 Exerts Pro‐Tumor Role in Glioblastoma via Inducing xCT/GPX4‐Regulated Ferroptosis
ABSTRACT Purpose This study investigates NR4A1's paradoxical roles in glioblastoma (GBM) progression, focusing on its mechanistic link to ferroptosis regulation. We aimed to resolve conflicting reports of NR4A1 as both an oncogene and a tumor suppressor by defining its transcriptional control over xCT/GPX4‐mediated iron homeostasis and its clinical ...
Peng Tao +10 more
wiley +1 more source
Origin and diversity of Capsella bursa-pastoris from the genomic point of view
Background Capsella bursa-pastoris, a cosmopolitan weed of hybrid origin, is an emerging model object for the study of early consequences of polyploidy, being a fast growing annual and a close relative of Arabidopsis thaliana.
Aleksey A. Penin +5 more
doaj +1 more source
What Can Genetic Relatedness Tell Us About Risk Factors for Tuberculosis Transmission?
Sarah V. Leavitt +5 more
openalex +2 more sources
A realistic transfer method reveals low risk of SARS-CoV-2 transmission via contaminated euro coins and banknotes [PDF]
Daniel Tödt +17 more
openalex +1 more source
SNUPN‐Related Muscular Dystrophy: Novel Phenotypic, Pathological and Functional Protein Insights
ABSTRACT Objective SNUPN‐related muscular dystrophy or LGMDR29 is a new entity that covers from a congenital or childhood onset pure muscular dystrophy to more complex phenotypes combining neurodevelopmental features, cataracts, or spinocerebellar ataxia. So far, 12 different variants have been described.
Nuria Muelas +18 more
wiley +1 more source
An Improved Algorithm for Noise Source Localization Based on Equivalent Source Method
Near-field acoustical holography (NAH) based on the equivalent source method (ESM) is an efficient method applied for noise source identification. As l2-norm-based regularization cannot produce a satisfactory solution of the ill-conditioned problem in ...
Zhongming Xu +5 more
doaj +1 more source
Detection and Characterization of Alongshan Virus in Ticks and Tick Saliva from Lower Saxony, Germany with Serological Evidence for Viral Transmission to Game and Domestic Animals [PDF]
Cara Leonie Ebert +23 more
openalex +1 more source
Decreased Serum 5‐HT: Clinical Correlates and Regulatory Role in NMJ of MG
ABSTRACT Objective Although 5‐Hydroxytryptamine (5‐HT) indirectly stimulates muscle contraction and participates in regulating Acetylcholine receptor (AChR) cluster homeostasis in cellular, animal, and clinical studies, evidence regarding its potential to modulate muscle contraction in myasthenia gravis (MG) remains limited.
Xinru Shen +18 more
wiley +1 more source
InvMOE: MOEs Based Invariant Representation Learning for Fault Detection in Converter Stations
Converter stations are pivotal in high-voltage direct current (HVDC) systems, enabling power conversion between an alternating current (AC) and a direct current (DC) while ensuring efficient and stable energy transmission.
Hao Sun +6 more
doaj +1 more source

