Results 21 to 30 of about 251,619 (265)

An Impact Location Method Based on Transmission Coefficient Weighted Impact Intensity

IEEE Access, 2020
The stiffened plate has complex influences on the propagation characteristics of Lamb waves, which causes difficulties for the impact location. In order to realize the impact location in stiffened plate, this paper proposes a transmission coefficient ...
Yu Zhang, Guixuan Yue, Xiaobo Rui, Lei Qi   +3 more
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Power Summation in an Open Resonator with Aperture Coupling Elements

Advanced Electromagnetics
The paper considers the powers summation of two sources in a hemispherical open resonator (OR). A scheme with a E- tee waveguide was used. The study was carried out in the four-millimeter wavelength range.
Igor K. Kuzmichev, Bogdan I. Muzychishin, Aleksey Y. Popkov, Sergey V. Mizrakhy   +3 more
doaj   +1 more source

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

FEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman, Katarzyna Stapor, Leszek Konieczny, Krzysztof Gądek, Piotr Nowakowski   +4 more
wiley   +1 more source

Tunable Transparency and Group Delay in Cavity Optomechanical Systems with Degenerate Fermi Gas

Photonics, 2023
We theoretically investigate the optical response and the propagation of an external probe field in a Fabry–Perot cavity, which consists of a mechanical mode of trapped, ultracold, fermionic atoms inside and simultaneously driven by an optical laser ...
Fatin Nadiah Yusoff, Muhammad Afiq Zulkifli, Norshamsuri Ali, Shailendra Kumar Singh, Nooraihan Abdullah, Nor Azura Malini Ahmad Hambali, Collins Okon Edet   +6 more
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende, Emilien Petit, Young Woo Park, Sophie Tezenas du Montcel, James M. Joers, Jonathan M. DuBois, H. Moore Arnold, Michal Povazan, Ipek Özdemir, Guita Banan, Romain Valabregue, Philipp Ehses, Jennifer Faber, Chiadi U. Onyike, Peter B. Barker, Jeremy D. Schmahmann, Eva‐Maria Ratai, Sub H. Subramony, Thomas H. Mareci, Khalaf O. Bushara, Henry Paulson, Thomas Klockgether, Alexandra Durr, Tetsuo Ashizawa, Christophe Lenglet, Gülin Öz, READISCA Investigators   +26 more
wiley   +1 more source

Microwave Sensor for Sodium Chloride Density Measurement in Aqueous Solutions

Journal of Engineering Technology and Applied Physics
Accurate determination of sodium chloride (NaCl) density in water is vital for assessing environmental impact, preventing soil salinization in agriculture, ensuring quality and consistency in industrial processes, facilitating medical treatments, and ...
Kim Ho Yeap, Jia Le Lam, Siu Hong Loh, Veerendra Dakulagi, Ahmad Uzair Mazlan   +4 more
doaj   +1 more source

Wave Transmision on Interlocking Concrete Block Submerged Breakwater

Jurnal Teknik Hidraulik, 2018
When a large dimension of rock needed for an armored layer of breakwater, the scarcity of it became a major adversity, because of that many research subject of using concrete as a substitute for rock performed.
I Ketut Dharma Setiawan
doaj   +1 more source

The Effect of Linker Group on Thermoelectric Properties of Dimer Zinc Porphyrin-Based Molecular Junctions

مجلة علوم ذي قار, 2023
The discovery of high-efficiency organic thermoelectric materials has the potential to pave the path for various energy-harvesting technologies and the development of flexible, transparent thin-film materials for Peltier coolers.
Dhia Preesam, Mohammed Noori, Hossain Moghaddam   +2 more
doaj   +1 more source