Results 41 to 50 of about 3,399,128 (304)
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Josephson Transmission Line Revisited
Herein, the series‐connected Josephson transmission line (JTL), constructed from Josephson junctions, capacitors, and (possibly) resistors, is considered. It is shown that the compact travelling waves in the lossy JTL are the shocks, some of their properties including their velocity are studied.
openaire +4 more sources
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Coupled CRLH transmission lines for compact and high selectivity bandpass filters [PDF]
A compact size and high selective bandpass filter is presented in this paper. The filter is designed to serve at 3.5 GHz with two transmission zeros at 3.35 GHz and 3.85 GHz.
Abdalla, M.A. +5 more
core +1 more source
In the hydro-rich areas with high proportion of hydropower in the transmission network, the capacity utilization of transmission lines varies seasonally due to the impact of hydropower abundance and depletion characteristics.
Yang LIU +5 more
doaj
Half-wavelength transmission can transmit large-scale renewable energy over very long distances. This paper proposes an improved steady-state voltage-control method for half-wavelength transmission systems considering large- scale wind-power transmission.
Hao Tian +5 more
doaj +1 more source
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil +3 more
wiley +1 more source
This study proposes a direct ZBUS three‐phase four‐wire power flow method to accurately analyse the neutral line and multiple grounding characteristics.
Nien‐Che Yang, Song‐Ting Zeng
doaj +1 more source

