Results 31 to 40 of about 625,137 (266)

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Design and Testing of a Gasoline Engine Muffler Based on the Principle of Split-Stream Rushing

open access: yesApplied Sciences
In order to reduce the exhaust noise, which is the main source of gasoline engine noise, this paper uses on orthogonal test to optimize the parameters of the main structure of split-stream rushing muffler (the perforation rate of the perforated pipe ...
Shiyi Ao   +7 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Analysis and Modelling on Radiated Noise of a Typical Fishing Boat Measured in Shallow Water Inspired by AQUO Project’s Model

open access: yesArchives of Acoustics, 2018
The shipping noise near channels and ports is an important contribution to the ambient noise level, and the depth of these sites is often less than 100 m.
Zilong PENG, Jun FAN, Bin WANG
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

A Novel Acoustic Ventilation Barrier Based on the Block-Shaped Space-Coiling Metamaterial

open access: yesApplied Sciences
Newly emerged acoustic barriers provide effective solutions for noise reductions of varied kinds in which acoustic barriers made of Fano resonance-based space-coiling metamaterial are reported to have promising application prospects for their broadband ...
Qiaoyun Wu   +4 more
doaj   +1 more source

An Improved MSA Model for Evaluating the Sound Transmission Loss of a Rectangular Plate for Diffuse Field Incidence

open access: yesArchives of Acoustics, 2019
This paper presents an approximate analytical model for estimating the transmission loss (TL) of a finite rectangular plate in the low frequency range, which is based on the modal summation approach (MSA) taking into account the modal radiation impedance
Myong-Jin KIM, Kyong-Su WON, Chol-Su RI
doaj   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Acoustic Propagation and Transmission Loss Analysis in Shallow Water of Northern Arabian Sea

open access: yesJournal of Marine Science and Engineering
This study investigates acoustic propagation and transmission loss in shallow water at an unexplored site in the northern Arabian Sea near the Pakistan coastline using a normal mode theoretical framework.
Shahabuddin Shaikh   +6 more
doaj   +1 more source

Electricity spot market with transmission losses

open access: yesJournal of Industrial & Management Optimization, 2013
In order to study deregulated electricity spot markets, various models have been proposed. Most of them correspond to a, so-called, multi-leader-follower game in which an Independent System Operator (ISO) plays a central role. Our aim in this paper is to consider quadratic bid functions together with the transmission losses in the multi-leader ...
Aussel, Didier   +2 more
openaire   +3 more sources

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