Results 51 to 60 of about 6,238,911 (308)

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Decoupling of voltage magnitude and phase in genetic algorithms for smart transmission network state estimation

Frontiers in Energy Research, 2023
A large amount of renewable energy resources are integrated into electricity transmission networks. For efficient operation, transmission networks should be smart, in which it is necessary to have the function of estimating the state of the power system.
Thanh-Son Tran, Thi-Thanh-Hoa Kieu, Duc-Tung Le   +2 more
doaj   +1 more source

Network modeling of BVD transmission [PDF]

Veterinary Research, 2012
Endemic diseases of cattle, such as bovine viral diarrhea, have significant impact on production efficiency of food of animal origin with consequences for animal welfare and climate change reduction targets. Many modeling studies focus on the local scale, examining the on-farm dynamics of this infectious disease.
Tinsley, Mark, Lewis, F I, Brülisauer, Franz   +2 more
openaire   +5 more sources

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Transmission network voltage stability assessment using a new line stability index [PDF]

هوش محاسباتی در مهندسی برق
Voltage stability assessment is one of the critical topics concerning the stability of power systems. With the increasing loading of transmission networks and its impact on downstream networks, the importance of studying this issue has gained attention ...
Seyed Eshagh Sadeghi, Asghar Akbari Foroud, Majid Shahabi   +2 more
doaj   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

Best practices to reduce methane emissions at gas transmission networks. A literature review and case studies

Green Energy and Sustainability, 2023
This paper studies methane emissions reduction at natural gas transmission systems. A literature survey on the topic is presented along with some characteristic case studies.
Artemis Tsochatzidi, Nikolaos A. Tsochatzidis   +1 more
doaj   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Spectrum Analysis of Contact Network for Public Policy in a Pandemic

IEEE Access, 2022
In a pandemic, in order to slow down the spread of the virus, protect national health, and maintain the normal operation of economic activities, countries around the world will formulate public policies to limit the number of citizens that can gather ...
Qi Xu
doaj   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

FEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source