Results 211 to 220 of about 3,081,004 (282)

Computational Modeling of Flow in an in Vitro Cerebrovascular Model Under Pulsatile Conditions with Experimental Validation. [PDF]

Cardiovasc Eng Technol
Su B, Craven BA, Kubicki CJ, Khalil D, Simon SD, Manning KB.   +5 more
europepmc   +1 more source

EDNRA Forms a Positive Feedback Loop with the Hippo/YAP Axis to Drive Triple‐Negative Breast Cancer Progression

Advanced Science, EarlyView.
Endothelin receptor type A (EDNRA) and the Hippo/YAP pathway form a self‐reinforcing loop that sustains triple‐negative breast cancer. EDNRA activates YAP through Gαq/11–Rho/ROCK–LATS signaling, while YAP/TEAD4 reciprocally drives EDNRA transcription.
Zehao Hong, Boyang Li, Jiahui Xu, Ruonan Lin, Jinghao Pan, Chenlu Fang, Boxiang Zhang, Lucy Yue Lau, Richard J. Aldridge, Elizabeth A. Whitmore, Yi Chen   +10 more
wiley   +1 more source

Comparative analysis of compressible solver schemes for underexpanded jet aerodynamics with Schlieren validation. [PDF]

Sci Rep
Alsaedi SS, Al-Sadawi LA, Al-Haddad LA, Abdul-Zahra AS, Odeh M, Flah A, Ogaili AAF.   +6 more
europepmc   +1 more source

Adaptation of Echinococcus Multilocularis to Oxidative Stress Depends on EmPDK‐Mediated Metabolic Reprogramming

Advanced Science, EarlyView.
Metabolic adaption presents a vital survival strategy for E. multilocularis. This study identifies EmPDK as a central metabolic regulator governing glucose metabolic reprogramming. Oxidative stress activates EmHIF1α to induce EmPDK expression. Mechanistic characterization reveals this ROS/EmHIF1α/EmPDK axis drives glycolytic reprogramming to sustain ...
Huijuan Wang, Zhijian Xu, Ye Tian, Yao Zhang, Zhe Cheng, Yanhai Wang   +5 more
wiley   +1 more source

Physically Consistent Resolving Simulations of Turbulent Flows. [PDF]

Entropy (Basel)
Heinz S.
europepmc   +1 more source

GeminiOne transcatheter edge-to-edge repair: comparative hemodynamic and biomechanical evaluation. [PDF]

Front Cardiovasc Med
Wang K, Xu D, Xiao B, He Z, Tan J, Kar S.   +5 more
europepmc   +1 more source

Graded response of the pulmonary circulation to progressive pulmonary embolism in sheep: From compensation to lethal right heart failure. [PDF]

JHLT Open
Zhou C, Li Y, Polley K, Ballard-Croft C, Kawabori M, Rajagopal K, Zwischenberger JB, Wang D.   +7 more
europepmc   +1 more source

Combined Apocynin and Novokinin Treatment Attenuates Renal Damage and Reduces KIM-1 Expression in a Model of Ischemic AKI. [PDF]

Int J Mol Sci
Ivanov M, Mihailović-Stanojević N, Vujačić UJ, Karanović D, Jovović D, Životić M, Kovacevic S, Nešović-Ostojić J, Miloradović Z.   +8 more
europepmc   +1 more source

Colchicine has Dose-Dependent Therapeutic Effects in a LPS-Induced Experimental Endotoxemia Model. [PDF]

Pharmacol Res Perspect
Demir M, Gocmen AY, Ozcelebi E, Doganyigit Z, Oflamaz AO, Iskit AB.   +5 more
europepmc   +1 more source

A Generalized Fisher Discriminant Analysis with Adaptive Entropic Regularization for Cross-Model Vibration State Monitoring in Wind Tunnels. [PDF]

Sensors (Basel)
Li Z, Li Z, Chen X, Lin H.
europepmc   +1 more source