Selective Inhibition of Integrin β3 Topology Provides a Safer Antithrombotic Strategy
Current integrin αIIbβ3 inhibitors effectively reduce thrombosis but also increase bleeding risk. During thrombosis, high shear blood flow can directly activate the integrin αIIbβ3 via a distinct topological change in the β3 transmembrane domain, independent of hemostatic platelet signaling.
Joonha Lee +11 more
wiley +1 more source
Enhanced external counter pulsation as a novel therapy to maintain cardiac output during hemodialysis: a preliminary randomized controlled study. [PDF]
Thongsricome T +6 more
europepmc +1 more source
This work proposes a multifunctional Bi2WO6:Yb,Er@CuS@CS nanocomposite that integrates photodynamic therapy (PDT), near‐infrared‐triggered photothermal therapy (PTT), and Cu2+ release for infected wound repair. The nanocomposite demonstrates enhanced antibacterial efficacy via combined PDT, PTT, and Cu2+ release, effective immunomodulatory by mild ...
Yihao Sun +9 more
wiley +1 more source
Dual therapy with vildagliptin and sacubitril/valsartan alleviates portal hypertension and inhibits soluble epoxide hydrolase in cirrhotic rats. [PDF]
Oyama M +12 more
europepmc +1 more source
Confinement by nanoscale covalent organic frameworks reinforces hydrogels, imparting exceptional mechanical strength and ionic conductivity for high‐performance electrolyte applications. ABSTRACT Hydrogels are widely applied in various fields, including energy storage and flexible electronics. However, their mechanical properties often fail to meet the
Peiyao Yan +15 more
wiley +1 more source
Air classification of copper granules from recycled electrical cables using a zig-zag separator. [PDF]
Madej P +3 more
europepmc +1 more source
Reverse-flow Thoracodorsal Artery: An Additional Perfusion Strategy for Breast Microsurgical Flaps. [PDF]
Longo B +7 more
europepmc +1 more source
Additional Carbon Dioxide Removal by Oxygenated Dialysis Fluid: Insights for the Development of a Novel Lung and Kidney Assist Device. [PDF]
Martins Costa A +4 more
europepmc +1 more source
Instrumentation Strategies for Monitoring Flow in Centrifugal Compressor Diffusers: Techniques and Case Studies. [PDF]
Prisăcariu EG, Dumitrescu O.
europepmc +1 more source
Concomitant Intracranial Aneurysm Clipping and Meningioma Resection: Surgical Strategy and Considerations. [PDF]
Atallah O, Alrefaie K, Badary A.
europepmc +1 more source

