Results 51 to 60 of about 547,876 (329)

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

The effect of medication cost transparency alerts on prescriber behavior

open access: yesJournal of the American Medical Informatics Association, 2019
Abstract Objective The purpose of this study was to determine if medication cost transparency alerts provided at time of prescribing led ambulatory prescribers to reduce their use of low-value medications.
Craig B Monsen   +4 more
openaire   +4 more sources

Tunable Broadband Transparency of Macroscopic Quantum Superconducting Metamaterials

open access: yesPhysical Review X, 2015
Narrow-band invisibility in an otherwise opaque medium has been achieved by electromagnetically induced transparency (EIT) in atomic systems. The quantum EIT behavior can be classically mimicked by specially engineered metamaterials via carefully ...
Daimeng Zhang   +3 more
doaj   +1 more source

Polydatin ameliorates ovalbumin‐induced asthma in a rat model through NCOA4‐mediated ferroautophagy and ferroptosis pathway

open access: yesFEBS Open Bio, EarlyView.
In this research, a rat model of asthma was created using OVA, and polydatin served as an intervention. By inhibiting ferroautophagy mediated by NCOA4 and averting ferroptosis, polydatin has been demonstrated to reduce asthma. This work presents new ideas for investigating the mechanism of polydatin's ability to alleviate asthma, in addition to ...
Wei Li   +5 more
wiley   +1 more source

Establishment and optimization of the two‐step induction system for generating primordial germ cell‐like cells from chicken embryonic stem cells

open access: yesFEBS Open Bio, EarlyView.
This study optimizes a two‐step induction system to generate PGCLCs from chicken ESCs. The induced cells express germline markers and migrate to gonads in ovo, offering a novel approach for avian genetic resource conservation. Primordial germ cells (PGCs) are the progenitor cells of sperm and eggs.
Zeyu Li   +10 more
wiley   +1 more source

Bio‐Macromolecular Surface Coatings for Autohesive, Transparent, Elastomeric Foils

open access: yesMacromolecular Materials and Engineering, 2023
Thin materials made from elastomeric polymers such as polydimethylsiloxane (PDMS) and polyurethane (PU) can be both, compliant and resilient. Their mechanical robustness and flexibility will make them great candidates for applications in the human body ...
Maria G. Bauer, Oliver Lieleg
doaj   +1 more source

The Road Not Taken: Misclassifying an Anti‐Seizure Medication as a Failure

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To quantify how often anti‐seizure medications (ASMs) appear ineffective yet provide benefit when considering seizure frequency (SF) variability. Methods We used the CHOCOLATES seizure diary simulator to generate 100,000 patient seizure diaries that reflect natural SF variation in a heterogeneous population.
Christopher N. Henry   +1 more
wiley   +1 more source

Influence of shear modulus on the behavior of acoustically transparent materials [PDF]

open access: yesThe Journal of the Acoustical Society of America, 1986
Materials are under development that match density (ρ) and dilatational sound speed (c) to the values of seawater as closely as possible while maintaining sufficient rigidity to serve for structural purposes. Another paper in this meeting by C. M. Thompson and J. R. Griffith (preceding abstract) describes the composition of the material and some of its
Kurt W. Rittenmyer, Pieter S. Dubbelday
openaire   +2 more sources

Impact of Reputation and Chief Executive Officer’s Job Security on Financial Reporting Transparency [PDF]

open access: yesمجله دانش حسابداری, 2019
Objective: Individual characteristics of chief executive officers, CEOs, such as reputation and job security may eclipse their behavior and types of decisions in the organization, and thereby affect the transparency of financial reporting.
Reza Taheri Abed (Ph.D)   +2 more
doaj   +1 more source

Home - About - Disclaimer - Privacy