Results 151 to 160 of about 2,546,887 (343)

Transcriptomic profiles of human livers undergoing rewarming machine perfusion before transplantation—first insights [PDF]

, 2021
Dieter P. Hoyer, Sandra M. Swoboda, Juergen Treckmann, Tamás Benkö, Andreas Paul, Nahal Brocke‐Ahmadinejad   +5 more
openalex   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

PD-1-Dependent Mechanisms Maintain Peripheral Tolerance of Donor-Reactive CD8+ T Cells to Transplanted Tissue [PDF]

, 2008
Brent H. Koehn, Mandy L. Ford, Ivana R. Ferrer, Keshawna Borom, Shivaprakash Gangappa, Allan D. Kirk, Christian P. Larsen   +6 more
openalex   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Does living donation have advantages over deceased donation in liver transplantation? [PDF]

, 2010
Toshimi Kaido, Shinji Üemoto
openalex   +1 more source

MELD 3.0 for adolescent liver transplant candidates [PDF]

, 2023
Allison J. Kwong, Ke‐You Zhang, Noelle H. Ebel, Ajitha Mannalithara, W. Ray Kim   +4 more
openalex   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Adipose tissue quantification and primary graft dysfunction after lung transplantation: The Lung Transplant Body Composition study [PDF]

, 2019
Michaela R. Anderson, Jayaram K. Udupa, Ethan A. Edwin, Joshua M. Diamond, Jonathan P. Singer, Jasleen Kukreja, Steven R. Hays, John R. Greenland, Anthony W. Ferrante, Matthew Lippel, Tatiana Blue, Amika McBurnie, M. Oyster, L. Kalman, Melanie Rushefski, Caiyun Wu, Gargi Pednekar, Wen Liu, Selim M. Arcasoy, Joshua Sonett, F. D’Ovidio, Matthew Bacchetta, John D. Newell, Drew A. Torigian, Edward Cantu, Donna L. Färber, Jon T. Giles, Yubing Tong, Scott M. Palmer, Lorraine B. Ware, Wayne W. Hancock, Jason D. Christie, David J. Lederer   +32 more
openalex   +1 more source

Long‐term culture of skin biopsies: maintenance of fibroblast production and competency of reprogramming

FEBS Open Bio, EarlyView.
Skin biopsies taken from a patient with an ultra‐rare disorder as well as controls were cultured for up to 473 days. The chunks of skin were serially transferred to a new culture plate when confluent with fibroblasts. Different generations of fibroblasts were analyzed for cell and molecular properties, proliferation, and competence for reprogramming to
Sudiksha Rathan‐Kumar, Michael A. Ripperger, Grant M. Westlake, Kevin C. Ess   +3 more
wiley   +1 more source

Harnessing the microbiome to improve clinical outcomes for cancer, transplant, and immunocompromised patients in the intensive care unit (ICU)

Frontiers in Cellular and Infection Microbiology
In recent decades, there has been a growing emphasis on understanding how the architecture of the human microbiome can impact typical biological processes and patient clinical outcomes. In fact, microbiome modifications and modulations have not only been
Lizbeth Nieves, Alexandra Roach, Joseph Hunter, Sarah Smeh, Andrew Islas, Ariana Islas, Joseph Blattman, Michelle Di Palma   +7 more
doaj   +1 more source