Results 91 to 100 of about 1,185,287 (314)

Myasthenia Gravis Treated With Autologous Hematopoietic Stem Cell Transplantation.

open access: yesJAMA Neurology, 2016
IMPORTANCE Some patients with myasthenia gravis (MG) do not respond to conventional treatment and have severe or life-threatening symptoms. Alternate and emerging therapies have not yet proved consistently or durably effective.
A. Bryant   +21 more
semanticscholar   +1 more source

Engineering CAR‐T Therapeutics for Enhanced Solid Tumor Targeting

open access: yesAdvanced Materials, EarlyView.
CART cell therapy has proven effective for blood cancers but struggles with solid tumors due to diverse antigens and complex environments. Recent efforts focus on improving CAR design and validation platforms. Advances in protein engineering, machine learning, and organoid systems aim to enhance CAR‐T therapy against solid tumors.
Danqing Zhu   +4 more
wiley   +1 more source

Regime and Treatment Effects in Duration Models: Decomposing Expectation and Transplant Effects on the Kidney Waitlist [PDF]

open access: yesarXiv, 2022
This paper proposes a causal decomposition framework for settings in which an initial regime randomization influences the timing of a treatment duration. The initial randomization and treatment affect in turn a duration outcome of interest. Our empirical application considers the survival of individuals on the kidney transplant waitlist.
arxiv  

Autologous transplantation and maintenance therapy in multiple myeloma.

open access: yesNew England Journal of Medicine, 2014
BACKGROUND This open-label, randomized, phase 3 study compared melphalan at a dose of 200 mg per square meter of body-surface area plus autologous stem-cell transplantation with melphalan-prednisone-lenalidomide (MPR) and compared lenalidomide ...
A. Palumbo   +26 more
semanticscholar   +1 more source

Materials Advances in Devices for Heart Disease Interventions

open access: yesAdvanced Materials, EarlyView.
This review examines the crucial role of materials in heart disease interventions, focusing on strategies for monitoring, managing, and repairing heart conditions. It discusses the material requirements for medical devices, highlighting recent innovations and their impact on cardiovascular health.
Gagan K. Jalandhra   +11 more
wiley   +1 more source

Hematopoietic stem cell transplantation for the management of follicular lymphoma

open access: yesStem Cells and Cloning: Advances and Applications, 2010
Chitra HosingDepartment of Stem Cell Transplantation and Cellular Therapy, The University of Texas M.D. Anderson Cancer Center, Houston, Texas, USAAbstract: Although much has been published on the application of autologous and allogeneic hematopoietic ...
Chitra Hosing
doaj  

An Initial Step Towards Organ Transplantation Based on GitHub Repository [PDF]

open access: yes, 2018
Organ transplantation, which is the utilization of codes directly related to some specific functionalities to complete ones own program, provides more convenience for developers than traditional component reuse. However, recent techniques are challenged with the lack of organs for transplantation.
arxiv   +1 more source

Current Advances of Antibacterial Biomaterials for Bone Regeneration

open access: yesAdvanced Materials Interfaces, EarlyView.
Effective treatment of infectious bone defects requires not only robust bone regeneration, but also the elimination of bacterial infection. This review highlights current cutting‐edge concepts and innovations in synthetic bone repair biomaterials and antibacterial bone repair materials, aiming to promote clinical translation and inspire broader ...
Xueping Kong   +3 more
wiley   +1 more source

Quantitative Methods for Optimizing Patient Outcomes in Liver Transplantation [PDF]

open access: yesarXiv, 2023
Liver transplantation continues to be the gold standard for treating patients with end-stage liver diseases. However, despite the huge success of liver transplantation in improving patient outcomes, long term graft survival continues to be a major problem.
arxiv  

Improved Outcomes After Autologous Hematopoietic Cell Transplantation for Light Chain Amyloidosis: A Center for International Blood and Marrow Transplant Research Study.

open access: yesJournal of Clinical Oncology, 2015
PURPOSE Autologous hematopoietic cell transplantation, or autotransplantation, is effective in light-chain amyloidosis (AL), but it is associated with a high risk of early mortality (EM).
A. D’Souza   +29 more
semanticscholar   +1 more source

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