Investigating Local Sequence‐Structural Attributes of Amyloidogenic Light Chain Variable Domains
ABSTRACT Light chain amyloidosis is a medical condition characterized by the aggregation of misfolded antibody light chains into insoluble amyloid fibrils in the target organs, causing organ dysfunction, organ failure, and death. Despite extensive research to understand the factors contributing to amyloidogenesis, accurately predicting whether a given ...
Puneet Rawat+6 more
wiley +1 more source
Corrigendum: Advancements in autologous peripheral nerve transplantation care: a review of strategies and practices to facilitate recovery. [PDF]
Xu G+10 more
europepmc +2 more sources
This study unveils a pioneering approach to bioengineering of human skin substitutes with distinct arterial and venous capillaries. Combining single‐cell transcriptomics and 3D hydrogel models, this work reveals unique endothelial marker dynamics in fetal and juvenile skin.
Dominic Rütsche+9 more
wiley +1 more source
Therapeutic efficacy of autologous bone marrow mesenchymal stem cell transplantation in patients with spinal cord injury: a meta-analysis. [PDF]
Liu Y, Xu W, Liu G, Ma L, Li Z.
europepmc +1 more source
Various properties of bone biomaterials can modulate components of the blood clot (including the fibrin network, red blood cells, platelets, and the complement system) in vivo implantation, leading to the formation of a biomaterial–blood clot complex (BBCC) significantly impacting subsequent osteoimmunomodulation.
Zongpu Han+11 more
wiley +1 more source
Hematopoietic Stem Cell Transplantation: Recent Advances. [PDF]
Milone G, Leotta S, Cupri A.
europepmc +1 more source
CRISPR/Cas9‐edited tumor‐associated immune cells in cancer immunotherapy
Abstract Immuno‐oncology represents an emerging field that has significantly transformed tumor therapeutics, with immune cells serving as the cellular foundations of cancer immunotherapy. Due to its high efficiency and sensitivity, CRISPR/Cas9 genome editing is a highly promising technique for precise and rapid gene modification.
Yuhui Ma+6 more
wiley +1 more source
Allogeneic versus autologous stem cell transplantation after relapsing following first line autologous transplantation for multiple myeloma: A systematic review. [PDF]
Ludwig H+11 more
europepmc +1 more source
Clinical Efficacy Analysis of Unilateral Modified Arytenoidectomy for Bilateral Vocal Fold Paralysis
ABSTRACT Purpose To explore the clinical efficacy of unilateral modified arytenoidectomy (UMA) in the treatment of bilateral vocal fold paralysis(BVFP) based on animal models. Methods The UMA which had been tested in excised canine larynges with simulated BVFP was adapted into a clinical technique. The characteristics of this surgical technique involve
Lu Xing, Shu‐Yi Zeng, Pei‐Yun Zhuang
wiley +1 more source
Case of Pulp Regeneration Following Autologous Transplantation of an Incompletely Rooted Tooth. [PDF]
Kimura H, Kumano T, Eida T.
europepmc +1 more source