Results 101 to 110 of about 166,647 (243)

Investigating Local Sequence‐Structural Attributes of Amyloidogenic Light Chain Variable Domains

open access: yesProteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Light chain amyloidosis is a medical condition characterized by the aggregation of misfolded antibody light chains into insoluble amyloid fibrils in the target organs, causing organ dysfunction, organ failure, and death. Despite extensive research to understand the factors contributing to amyloidogenesis, accurately predicting whether a given ...
Puneet Rawat   +6 more
wiley   +1 more source

Corrigendum: Advancements in autologous peripheral nerve transplantation care: a review of strategies and practices to facilitate recovery. [PDF]

open access: yesFront Neurol
Xu G   +10 more
europepmc   +2 more sources

Human Dermal Microvascular Arterial and Venous Blood Endothelial Cells and Their Use in Bioengineered Dermo‐Epidermal Skin Substitutes

open access: yesSmall Methods, EarlyView.
This study unveils a pioneering approach to bioengineering of human skin substitutes with distinct arterial and venous capillaries. Combining single‐cell transcriptomics and 3D hydrogel models, this work reveals unique endothelial marker dynamics in fetal and juvenile skin.
Dominic Rütsche   +9 more
wiley   +1 more source

The Biomaterial and Blood Clot Complex: A Crucial Early Environment for Osteo‐Coagulo‐Immunomodulation and the Advancement of Bone Biomaterials

open access: yesSmall Structures, EarlyView.
Various properties of bone biomaterials can modulate components of the blood clot (including the fibrin network, red blood cells, platelets, and the complement system) in vivo implantation, leading to the formation of a biomaterial–blood clot complex (BBCC) significantly impacting subsequent osteoimmunomodulation.
Zongpu Han   +11 more
wiley   +1 more source

CRISPR/Cas9‐edited tumor‐associated immune cells in cancer immunotherapy

open access: yesVIEW, EarlyView.
Abstract Immuno‐oncology represents an emerging field that has significantly transformed tumor therapeutics, with immune cells serving as the cellular foundations of cancer immunotherapy. Due to its high efficiency and sensitivity, CRISPR/Cas9 genome editing is a highly promising technique for precise and rapid gene modification.
Yuhui Ma   +6 more
wiley   +1 more source

Allogeneic versus autologous stem cell transplantation after relapsing following first line autologous transplantation for multiple myeloma: A systematic review. [PDF]

open access: yesCancer
Ludwig H   +11 more
europepmc   +1 more source

Clinical Efficacy Analysis of Unilateral Modified Arytenoidectomy for Bilateral Vocal Fold Paralysis

open access: yesWorld Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Purpose To explore the clinical efficacy of unilateral modified arytenoidectomy (UMA) in the treatment of bilateral vocal fold paralysis(BVFP) based on animal models. Methods The UMA which had been tested in excised canine larynges with simulated BVFP was adapted into a clinical technique. The characteristics of this surgical technique involve
Lu Xing, Shu‐Yi Zeng, Pei‐Yun Zhuang
wiley   +1 more source

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