Results 131 to 140 of about 1,185,287 (314)

Effectiveness of Autologous Hematopoietic Stem Cell Transplantation versus Alemtuzumab and Ocrelizumab in Relapsing Multiple Sclerosis: A Single Center Cohort Study

open access: yesAnnals of Neurology, EarlyView.
Objective To compare clinical and radiological outcomes among relapsing multiple sclerosis patients treated with autologous hematopoietic stem cell transplantation (AHSCT), alemtuzumab (ATZ), and ocrelizumab (OCR). Methods From a London (UK) hospital‐based observational cohort, modeled data were obtained from 621 relapsing–remitting multiple sclerosis ...
Paolo Antonio Muraro   +16 more
wiley   +1 more source

Changing gears: Isospectrality via eigenderivative transplantation [PDF]

open access: yesarXiv, 2015
We introduce a new method for constructing isospectral quantum graphs that is based on transplanting derivatives of eigenfunctions. We also present simple digraphs with the same reversing zeta function, which generalizes the Bartholdi zeta function to digraphs.
arxiv  

Breaking barriers: Smart vaccine platforms for cancer immunomodulation

open access: yesCancer Communications, EarlyView.
Abstract Despite significant advancements in cancer treatment, current therapies often fail to completely eradicate malignant cells. This shortfall underscores the urgent need to explore alternative approaches such as cancer vaccines. Leveraging the immune system's natural ability to target and kill cancer cells holds great therapeutic potential ...
Mohammad Mahmoudi Gomari   +11 more
wiley   +1 more source

Guided transpositional bone blocks in esthetic zone: Surgical technique and case report

open access: yesClinical Advances in Periodontics, EarlyView.
Abstract Background The ultimate objective of implant dentistry is to position the implant in a three‐dimensional, prosthetic‐driven location. This case highlights a guided approach for harvesting and positioning an autogenous bone block to restore a horizontal bone defect in the anterior maxilla.
Ming‐Fu Ye   +5 more
wiley   +1 more source

AutoLogi: Automated Generation of Logic Puzzles for Evaluating Reasoning Abilities of Large Language Models [PDF]

open access: yesarXiv
While logical reasoning evaluation of Large Language Models (LLMs) has attracted significant attention, existing benchmarks predominantly rely on multiple-choice formats that are vulnerable to random guessing, leading to overestimated performance and substantial performance fluctuations.
arxiv  

A comparison of early fixation of distal radius fractures versus late corrective osteotomy of distal radius malunion

open access: yesANZ Journal of Surgery, Volume 92, Issue 12, Page 3319-3324, December 2022., 2022
Fractures of the distal radius are common, however in circumstances whereby the patient may require surgical intervention, it is unclear if necessitated late surgery will provide similar outcomes as early intervention. We performed a single centre, age matched, retrospective cohort comparison study, comparing outcomes of patients who had undergone ...
Conor Gouk   +5 more
wiley   +1 more source

Survival tree and meld to predict long term survival in liver transplantation waiting list [PDF]

open access: yesarXiv, 2008
Background: Many authors have described MELD as a predictor of short-term mortality in the liver transplantation waiting list. However MELD score accuracy to predict long term mortality has not been statistically evaluated. Objective: The aim of this study is to analyze the MELD score as well as other variables as a predictor of long-term mortality ...
arxiv  

Magnetic resonance imaging during warm ex vivo kidney perfusion

open access: yesArtificial Organs, Volume 47, Issue 1, Page 105-116, January 2023., 2023
Abstract Background The shortage of donor organs for transplantation remains a worldwide problem. The utilization of suboptimal deceased donors enlarges the pool of potential organs, yet consequently, clinicians face the difficult decision of whether these sub‐optimal organs are of sufficient quality for transplantation. Novel technologies could play a
Rianne Schutter   +9 more
wiley   +1 more source

EVALUATION OF COMMON INTERACTIONS INCLUDING ANTI-INFECTIVE DRUGS IN PATIENTS UNDERWENT AUTOLOGOUS AND ALLOGENEIC STEM CELL TRANSPLANTATION

open access: yesHematology, Transfusion and Cell Therapy, 2021
Objective: Hematopoietic stem cell transplantation is a challenging process involving polypharmacy. Drug-drug interactions are common due to the large number of drugs used in patients, and antiinfectives are frequently involved in interactions due to ...
Ayse Gunay, Eren Demirpolat, Ali Unal
doaj  

Mitochondrial targets in ischaemic heart disease and heart failure, and their potential for a more efficient clinical translation. A scientific statement of the ESC Working Group on Cellular Biology of the Heart and the ESC Working Group on Myocardial Function

open access: yesEuropean Journal of Heart Failure, EarlyView.
Improving clinical translation of mitoprotective therapies. 31P MRI, phosphorus‐31 magnetic resonance imaging; hiPSC‐CM, human‐induced pluripotent stem cell‐derived cardiomyocyte; IHD, ischaemic heart disease. Abstract Acute myocardial infarction (MI) remains a major cause of death and disability worldwide.
Melanie Paillard   +29 more
wiley   +1 more source

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