Results 131 to 140 of about 181,664 (310)
Autologous transplantation of lung progenitor cells comes into reality for bronchiectasis
Cell Reports MedicineStem and progenitor cell-based regenerative therapies have the potential to cure chronic respiratory diseases. Yan et al.1 reported a clinical trial of autologous P63+ progenitor cell transplantation in bronchiectasis patients, highlighting autologous ...
Jun-qing Yue, Rui-di Tang, Wei-jie Guan
doaj +1 more source
Force stimulation promotes nerve regeneration by restoring cellular energy
BMEMat, EarlyView.Mechanical stimulation can help nerves regenerate in various ways. We developed two devices (a piezo‐motor‐driven stretching device and a SAW‐based actuator) to apply mechanical stimulation to sciatic nerve and DRG neurons. Our study shows that appropriate mechanical force stimulation can promote regeneration by restoring the energy supply to the ...
Zhe Wang +10 more
wiley +1 more source
The ageing holobiont: crosstalk between telomere dynamics, oxidative stress and the gut microbiome
Biological Reviews, EarlyView.ABSTRACT The gut tissue is at the frontline of early onset of ageing. It exhibits high cell turnover rates and rapid telomere shortening, which can have systemic effects on the developing or senescing organism. We conducted a literature review of studies on the crosstalk between telomere length dynamics, telomerase activity, oxidative stress, and gut ...
Michael L. Pepke +2 more
wiley +1 more source
Clinical Advances in Periodontics, EarlyView.Abstract Background Loss of the interdental papilla compromises esthetics, speech, and hygiene, significantly affecting quality of life and psychological well‐being. Reconstruction has long been considered unpredictable, particularly in Cairo RT3 cases with advanced interproximal bone loss.
Katsuhiko Akiyama
wiley +1 more source
Autologous chondrocyte implantation for cartilage repair: current perspectives
Orthopedic Research and Reviews, 2015 Johannes Zellner,1 Werner Krutsch,1 Christian G Pfeifer,1 Matthias Koch,1 Michael Nerlich,1 Peter Angele1,2 1Department of Trauma Surgery, University Medical Center Regensburg, Regensburg, Germany; 2Sporthopaedicum, Regensburg, Germany Abstract: Over ...
Zellner J +5 more
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Clinical Advances in Periodontics, EarlyView.Abstract Background The aim of the study is to report clinical outcomes of autogenous tooth transplantation (ATT) of fully developed third molars following the extraction of periodontally hopeless teeth as a part of the treatment of a stage III, grade C, molar‐incisor pattern (MIP) periodontitis case.
Alessandro Rizzi +3 more
wiley +1 more source
Novel Organelle‐Based Intracellular Immunity With Mechanistic and Therapeutic Implications
Barrier Immunity, EarlyView.A conceptual framework illustrating how PAMPs/DAMPs initiate barrier, innate, adaptive, and intracellular immune responses, with organelle‐based intracellular immunity serving as a central integrator linking metabolism, inflammatory signaling, and therapeutic interventions to restore immune homeostasis.
Keman Xu +9 more
wiley +1 more source
Developmental Dynamics, EarlyView.Abstract Background Schwann cells provide peripheral nerve trophic support, myelinate axons, and assist in repair. However, Schwann cell repair capacity is limited by chronic injury, disease, and aging. Schwann cell reprogramming is a cellular conversion strategy that could provide a renewable cell supply to repair injured nerves.
Lauren Belfiore +7 more
wiley +1 more source
ESC Heart Failure, Volume 12, Issue 2, Page 1455-1463, April 2025.Abstract Aims The extent of irreversible cardiomyocyte necrosis after acute myocardial infarction (AMI) is a major determinant of residual left ventricular (LV) function and clinical outcome. Cell therapy based on CD34+ cells has emerged as an option to help repair the myocardium and to improve outcomes.
Jerome Roncalli +17 more
wiley +1 more source