Results 61 to 70 of about 92,223 (198)

rWTC‐MBTA Vaccine, Alone and Enhanced with Anti‐PD1, Elicits Immune Responses against CNS and Peripheral B‐Cell Lymphoma

Advanced Science, EarlyView.
An autologous whole‐tumor‐cell vaccine (rWTC‐MBTA) is evaluated in murine CNS lymphoma. Subcutaneous vaccination activates dendritic cells, broadens T‐cell priming, and drives lymphocyte trafficking to brain tumors, producing durable tumor control. Longitudinal bioluminescence and adoptive‐transfer assays verify CNS engagement. Combination with anti‐PD‐
Yaping Zhang, Juan Ye, Mitchell Sun, Samik Chakraborty, Alex Valenzuela, Shuran Chen, Qingfeng Xue, Wenyu Shi, Karel Pacak, Herui Wang, Zhengping Zhuang   +10 more
wiley   +1 more source

Two Methods for Meniscus Transplantation: Allograft Meniscus Transplantation and Autologous Tendon Transplantation

Formosan Journal of Musculoskeletal Disorders
This review compares two main methods of knee meniscus transplantation: allograft meniscus transplantation and autologous tendon transplantation. Allograft meniscus transplantation, developed in the 1970s, is effective but costly.
Po-Chun Chi, Yu-Che Lee, Alvin Chao-Yu Chen, Yi-Sheng Chan, Cheng-Pang Yang   +4 more
doaj   +1 more source

Parabiosis, Assembloids, Organoids (PAO)

Advanced Science, EarlyView.
This review evaluates parabiosis, organoids, and assembloids as complementary disease models spanning systemic, organ, and multi‐organ levels. It highlights their construction strategies, applications, and current limitations, while emphasizing their integration with frontier technologies such as artificial intelligence, organ‐on‐a‐chip, CRISPR, and ...
Yang Hong, Lavonda Li, Lijie Yan, Long Bai, Jiacan Su, Xingcai Zhang   +5 more
wiley   +1 more source

Clinical Summary of 186 Cases of Orbital Autologous Fat Injection Transplantation Safely Implemented by Boosters

Xiehe Yixue Zazhi
ObjectiveTo summarize the clinical effect of using boosters for orbital autologous fat injection transplantation.MethodsA retrospective analysis was conducted on the clinical data of patients who underwent orbital fine autologous fat injection and ...
LIU Ping, LIU Yi, SONG Mei, YANG Fuxiu, LI Xiaoxiao, WANG Yinping   +5 more
doaj   +1 more source

A Lung‐Immune Dual‐Humanized Mouse Using Cryopreserved Tissue Enables Infection and Immune Profiling of Human Common Cold Coronaviruses

Advanced Science, EarlyView.
Cryopreserved lung‐humanized mice overcome the dependency to fresh tissues and permit head‐to‐head profiling of all four human common cold coronaviruses versus SARS‐CoV‐2 infection; the model validates Paxlovid efficacy against HKU1 and, when coupled with human immune‐system engraftment, enables interrogation of lung‐resident human immunity and HKU1 ...
Chunyu Cheng, Jing Sun, Chun Lu, Qian Yu, Yiyun He, Bingqing Wu, Deshan Ren, Shuai Ding, Jincun Zhao, Yan Li   +9 more
wiley   +1 more source

Age and lymphocyte/monocyte ratio as prognostic factors for autologous transplantation in the treatment of patients with follicular lymphoma

Journal of International Medical Research
Objective Follicular lymphoma (FL) is an indolent, lymphoproliferative disease of B-cell origin that has a heterogeneous disease course with varying outcomes. Certain patients may undergo autologous stem cell transplantation.
Anna Kenyeres, Evelin Kiss, Zsófia Simon, Árpád Illés, Ádám Jóna   +4 more
doaj   +1 more source

Persistent seropositivity for yellow fever in a previously vaccinated autologous hematopoietic stem cell transplantation recipient

International Journal of Infectious Diseases, 2015
The duration of a protective level of yellow fever antibodies after autologous hematopoietic stem cell transplantation in a previously vaccinated person is unclear.
Kayoko Hayakawa, Tomohiko Takasaki, Hiroko Tsunemine, Shuzo Kanagawa, Satoshi Kutsuna, Nozomi Takeshita, Momoko Mawatari, Yoshihiro Fujiya, Kei Yamamoto, Norio Ohmagari, Yasuyuki Kato   +10 more
doaj   +1 more source

Targeted 2‐Deoxy‐D‐Ribose Delivery by Biomimetic Nanoplatform Activates EGFR for Accelerated Heart Valve Endothelialization

Advanced Science, EarlyView.
This study develops a biomimetic nanoplatform using erythrocyte membrane‐camouflaged, CD144 antibody‐functionalized nanoparticles to deliver 2‐deoxy‐D‐ribose (2dDR). This system promotes heart valve endothelialization by enhancing endothelial cell migration and proliferation via EGFR activation, while improving hemocompatibility.
Xiang Qiu, Gaofeng Li, Wenyi Wan, Jinsheng Li, Ge Yan, Shijie Wang, Xiuqi Hu, Zongqi Han, Yazheng Shan, Ying Zhou, Nianguo Dong, Weihua Qiao   +11 more
wiley   +1 more source

Evaluation of the Repair of Bone Defect after Bone Marrow Stromal Cell Transplantation in Rat

Journal of Fasa University of Medical Sciences, 2013
Background & Objective: Bone marrow stromal cells (BMSCs) are multipotent stem cells that can proliferate and differentiate into osteogenic cells . T his study aimed to investigate the effects of BMSC transplantation for the repair of bone defects in the
Roghayeh Rezaei, Soheila Ebrahimi, Seyyed Homayoun Sadraie, Majid Naghdi, Giti Torkaman, Zabihollah Hasanzadeh, Gholamreza Kaka   +6 more
doaj  

Modulating Integrin and Growth Factor Signaling With Peptides: Strategies to Synergistically Enhance Bone Tissue Regeneration

Advanced Science, EarlyView.
It has been demonstrated that, in the bone extracellular matrix (ECM), integrins and growth factor receptors (GFRs) engage in synergistic signaling to guide bone healing and regeneration. This review provides a comprehensive overview of current strategies using ECM‐derived peptides to recreate the cellular microenvironment and harness synergistic ...
Lluís Oliver‐Cervelló, Elisabetta Ada Cavalcanti‐Adam, Carlos Mas‐Moruno   +2 more
wiley   +1 more source