Results 61 to 70 of about 1,252,849 (358)

Phase I Clinical Trial of Autologous Stem Cell–Sheet Transplantation Therapy for Treating Cardiomyopathy

Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease, 2017
Background When transplanted into failing heart, autologous somatic tissue–derived cells yield functional recovery via paracrine effects that enhance native regeneration. However, the therapeutic effects are modest.
S. Miyagawa, Keitaro Domae, Y. Yoshikawa, S. Fukushima, Teruya Nakamura, Atsuhiro Saito, Y. Sakata, S. Hamada, K. Toda, K. Pak, M. Takeuchi, Y. Sawa   +11 more
semanticscholar   +1 more source

Phase 2 results of lisocabtagene maraleucel in Japanese patients with relapsed/refractory aggressive B‐cell non‐Hodgkin lymphoma

Cancer Medicine, Volume 11, Issue 24, Page 4889-4899, December 2022., 2022
This analysis assessed safety and efficacy of lisocabtagene maraleucel (liso‐cel), an autologous CD‐19‐directed CAR T‐cell product, in Japanese patients with R/R aggressive LBCL in Cohort 3 of TRANSCEND WORLD (NCT03484702). Liso‐cel demonstrated meaningful efficacy and a manageable safety profile in Japanese patients with R/R LBCL.
Shinichi Makita, Go Yamamoto, Dai Maruyama, Yuki Asano‐Mori, Daisuke Kaji, Revathi Ananthakrishnan, Ken Ogasawara, Lara Stepan, Claudia Schusterbauer, Nils Rettby, Jens Hasskarl, Koji Izutsu   +11 more
wiley   +1 more source

New perspectives to repair a broken heart [PDF]

, 2009
The aim of cardiac cell therapy is to restore at least in part the functionality of the diseased or injured myocardium by the use of stem/ progenitor cells.
BARILE, Lucio, CHIMENTI, ISOTTA, DI CONSIGLIO, ALBERTO, FORTE, ELVIRA, FRATI, GIACOMO, GAETANI, ROBERTO, GIACOMELLO, Alessandro, IONTA, VITTORIA, MESSINA, ELISA, MIRALDI, Fabio   +9 more
core   +1 more source

Predicting Kidney Transplant Survival using Multiple Feature Representations for HLAs [PDF]

Proceedings of the 19th International Conference on Artificial Intelligence in Medicine (2021) 51-60, 2021
Kidney transplantation can significantly enhance living standards for people suffering from end-stage renal disease. A significant factor that affects graft survival time (the time until the transplant fails and the patient requires another transplant) for kidney transplantation is the compatibility of the Human Leukocyte Antigens (HLAs) between the ...
arxiv  

Transplantation with autologous bone marrow‐derived mesenchymal stem cells for alcoholic cirrhosis: Phase 2 trial

Hepatology, 2016
Bone marrow‐derived mesenchymal stem cell (BM‐MSC) transplantation has been suggested as an effective therapy for liver cirrhosis. The efficacy and safety of autologous BM‐MSC transplantation in the treatment of alcoholic cirrhosis were investigated ...
K. Suk, Jung‐Hwan Yoon, M. Kim, C. Kim, J. Kim, Han-Soo Park, Seong-Gyu Hwang, D. J. Kim, Byung Seok Lee, Sae-Hwan Lee, Hong Soo Kim, J. Jang, C. Lee, B. S. Kim, Y. Jang, M. Cho, Eun-Sun Jung, Yong Man Kim, S. Bae, S. Baik   +19 more
semanticscholar   +1 more source

Single or tandem autologous stem-cell transplantation for first-relapsed or refractory Hodgkin lymphoma: 10-year follow-up of the prospective H96 trial by the LYSA/SFGM-TC study group

Haematologica, 2016
We assessed the long-term results of autologous stem-cell transplantation for patients with first-relapsed or refractory Hodgkin lymphoma included in the prospective Lymphoma Study Association/Société Française de Greffe de Moelle H96 trial.
David Sibon, Franck Morschhauser, Matthieu Resche-Rigon, David Ghez, Jehan Dupuis, Ambroise Marçais, Bénédicte Deau-Fischer, Reda Bouabdallah, Catherine Sebban, Gilles Salles, Pauline Brice   +10 more
doaj   +1 more source

A Review of Autologous Islet Transplantation [PDF]

Cell Medicine, 2013
Autologous islet transplantation after total or semitotal pancreatectomy aims to preserve insulin secretory function and prevent the onset of diabetes. The major indication for pancreatectomy is chronic pancreatitis with severe abdominal pain, a benign pancreatic tumor, and trauma.
K. Otsuki, Ikuko Matsumoto, Takashi Kenmochi, Michihiro Maruyama, Naotake Akutsu, Taihei Ito, Takehide Asano   +6 more
openaire   +3 more sources

Mesenchymal stem cells: A novel treatment option for primary sclerosing cholangitis

Cell Biology International, Volume 47, Issue 2, Page 467-479, February 2023., 2023
Abstract Primary sclerosing cholangitis (PSC) is a progressive liver disease for which there is no effective therapy. Hepatocytes and cholangiocytes from a PSC patient were cocultured with mesenchymal stem cells (MSCs) to assess in vitro change. A single patient with progressive PSC was treated with 150 million MSCs via direct injection into the common
Amy L. Lightner, Neda Dadgar, Anil Vaidya, Robert Simon, Clifton Fulmer, Hassan Siddiki, K. V. Narayanan Menon, Peter Liu, R. Matthew Walsh   +8 more
wiley   +1 more source

Comparison of Intracardiac Cell Transplantation: Autologous Skeletal Myoblasts Versus Bone Marrow Cells

Circulation, 2003
Background—Multiple cell types are being proposed for cardiac repair, but side-by-side comparisons are lacking. We tested the hypothesis that intracardiac transplantation of autologous bone marrow- or skeletal muscle-derived progenitor cells improve ...
Richard B. Thompson, S. Emani, B. Davis, E. J. van den Bos, Y. Morimoto, D. Craig, D. Glower, Doris A Taylor   +7 more
semanticscholar   +1 more source

Combination of Deauville score and quantitative positron emission tomography parameters as a predictive tool of anti‐CD19 chimeric antigen receptor T‐cell efficacy

Cancer, Volume 129, Issue 2, Page 255-263, 15 January 2023., 2023
Abstract Background Autologous anti‐CD19 chimeric antigen receptor (CAR) T‐cell therapy is an effective treatment for approximately 40% of relapsed/refractory large B cell lymphomas (LBCL), and early identification of patients at risk for relapse or progression after CAR T‐cell therapy represents a clinical need.
Anna Guidetti, Anna Dodero, Alice Lorenzoni, Sara Pizzamiglio, Giovanni Argiroffi, Annalisa Chiappella, Filippo Bagnoli, Vincenzo Marasco, Cristiana Carniti, Chiara Monfrini, Ettore Seregni, Martina Pennisi, Paolo Verderio, Alessandra Alessi, Paolo Corradini   +14 more
wiley   +1 more source