Organoid Models to Study Human Infectious Diseases
Our manuscript reviews the role of organoids as models for studying human infectious diseases, highlighting their irreplaceable contributions to drug testing and vaccine development for significant infectious diseases including HIV, ZIKV, SARS‐CoV‐2 and MPXV.
Sijing Zhu+4 more
wiley +1 more source
Patient Blood Management in pediatric and adolescent bone marrow donors: results from an Italian survey. [PDF]
Fante CD+5 more
europepmc +1 more source
Transcriptional and translational characteristics during goat oocyte maturation and identification of key factors, including GTPBP4, for prepubertal goat oocyte maturation. ABSTRACT The intricate mechanisms driving oocyte maturation remain only partially understood, especially within the domains of domestic animal reproduction and translational ...
Jianpeng Qin+21 more
wiley +1 more source
Second allogeneic stem cell transplantation using different donors as the salvage treatment for acute myeloid leukemia relapsed after allogeneic hematopoietic stem cell transplantation. [PDF]
Liu Z+7 more
europepmc +1 more source
This article elaborates on the role of NK cells in early pregnancy from multiple perspectives, including molecular mechanisms and therapeutic interventions. It also discusses how NK cell dysfunction contributes to RSA and RIF, aiming to provide insights for future research on NK cell mechanisms and clinical treatment of RSA and RIF.
Defeng Guan+5 more
wiley +1 more source
Applications of CRISPR-Cas-Based Genome Editing Approaches Against Human Cytomegalovirus Infection. [PDF]
Zhang A, Zhang I, Liu F.
europepmc +1 more source
Research Advances of the Autophagy‐Regulated Radiosensitivity
Autophagy plays a dual role in regulating cellular radiosensitivity in radiotherapy (RT). We discuss the mechanisms by which autophagy promotes survival and growthsuppression by modulating radiosensitivity. It also outlines some frontier autophagy‐targeted radiotherapies. ABSTRACT Autophagy is an evolutionarily conserved process of cell self‐catabolism
Hanyue Liu+7 more
wiley +1 more source
Artificial blood vessels-clinical development of TEVG. [PDF]
Itoh M, Kamohara K, Node K, Nakayama K.
europepmc +1 more source
Macrophage Efferocytosis as a Therapeutic Strategy in Intervertebral Disc Degeneration
Macrophages, integral to degenerated intervertebral discs, play a critical role in disc degeneration. By performing efferocytosis, they clear apoptotic cells. This article explores the process of efferocytosis, its molecular mechanisms, potential therapeutic implications for intervertebral disc degeneration and future strategies for targeted treatments.
Shijie Chen+9 more
wiley +1 more source
Mitochondrial Transplantation/Transfer: Promising Therapeutic Strategies for Spinal Cord Injury. [PDF]
Xiong X+8 more
europepmc +1 more source