Results 141 to 150 of about 73,189 (295)
British Journal of Haematology, EarlyView.Inherited thrombocytopenia (IT) caused by germline variants in RUNX1, ETV6 or ANKRD26 carries a high risk of developing haematological malignancy. This study examined the clinical, platelet and molecular characteristics of 66 patients with these conditions, who carried 24 distinct genetic variants in the corresponding genes.
Ana Marín‐Quílez +34 more
wiley +1 more source
Beyond synapses: cytoplasmic connections in brain function and evolution
Biological Reviews, EarlyView.ABSTRACT Following Ramón y Cajal's groundbreaking contributions to the identification of synapses, research in neuroscience predominantly focused on their pivotal role in neural communication (the neuron doctrine), overlooking an intriguing possibility suggested by Golgi of non‐synaptic interactions among neural cells.
Malalaniaina Rakotobe, Chiara Zurzolo
wiley +1 more source
WERF Endometriosis Phenome and Biobanking Harmonisation Project for Experimental Models in Endometriosis Research (EPHect-EM-Homologous): homologous rodent models. [PDF]
Mol Hum ReprodBurns KA +18 more
europepmc +1 more source
Effect of ribonucleic acid perfusion on canine kidney and liver homograft survival. [PDF]
, 1968 Brettschneider, L +6 more
core
Re‐make, re‐model: evolution and development of vertebrate cranial lateral lines
Biological Reviews, EarlyView.ABSTRACT Lateral lines are placodally derived mechanosensory systems on the heads and trunks of many aquatic vertebrates. There is evidence of lateral lines in the earliest known vertebrate fossils, and they exist in organisms with widely different craniofacial morphologies – including the presence or absence of jaws, external or internal nostrils, and
Vishruth Venkataraman +3 more
wiley +1 more source
Stem Cell Transplantation for Ovarian Cancer Patient with Associated Myelodysplasia After Maintenance Therapy with Olaparib: A Case Report. [PDF]
Int Med Case Rep JLinn Z, Gu Z, Wang L, Cai S.
europepmc +1 more source
Cancer Science, EarlyView.This study developed a genetically engineered and transplantable cholangiocarcinoma (CCA) organoid model in immunocompetent mice to investigate the role of tumor‐infiltrating immune cells in CCA progression. The findings revealed that tumor‐infiltrating neutrophils (TINs) exhibit antitumor activity by directly killing cancer cells through reactive ...
Osamu Sugahara +6 more
wiley +1 more source
LATS1/2–Integrin Axis Confers Tumor‐Generated Forces That Activate Neighboring Fibroblasts
Cancer Science, EarlyView.This study shows that LATS1/2 kinases in cancer cells regulate mechanical forces and fibroblast activation in tumors. Deleting LATS1/2 disrupts force generation and collagen matrix organization, highlighting the Hippo pathway as a potential target for cancer therapy.
Yanliang Liu +10 more
wiley +1 more source