Results 141 to 150 of about 39,144 (247)

YKT6 Is Essential for Male Fertility by Promoting Meiosis Progression During Spermatogenesis of Mice

Cell Proliferation, EarlyView.
Specifically ablating Ykt6 in pre‐meiotic germ cells and meiotic spermatocytes leads to complete sterility and meiotic arrest in conditional knockout male mice. YTK6 is required for stabilising intercellular bridges between spermatocytes due to its key role in maintaining protein homeostasis and vesicular transport‐dependent functions in spermatocytes,
Jie Cen, Xiaochen Yu, Ziqi Wang, Wenbo Liu, Jianze Xu, Qian Fang, Fei Gao, Yongzhi Cao, Hongbin Liu   +8 more
wiley   +1 more source

Preliminary high-dose irradiation of the recipient and associated damage of bone marrow stromal compartment enables bone marrow stroma transplantation. [PDF]

Sci Rep
Bigildeev A, Bigildeev E, Bulygina E, Tsygankova S, Gusakova M, Illarionova O.   +5 more
europepmc   +1 more source

PRACTICAL METHODS OF HOMOLOGOUS CARDIAC TRANSPLANTATION

Journal of Thoracic Surgery, 1959
Watts R. Webb, Hector S. Howard, William A. Neely, Stennis Wax, Dyke Hagaman   +4 more
openaire   +2 more sources

Survival of homologous transplants of neonatal kidneys in dogs

Transplantation, 1964
M. Claman, J. Balfour, D. Forbes
openaire   +4 more sources

CRISPR Technology in Disease Management: An Updated Review of Clinical Translation and Therapeutic Potential

Cell Proliferation, EarlyView.
CRISPR‐Cas systems offer transformative genome editing capabilities for precise manipulation of cellular genes. This enables two main therapeutic avenues: ex vivo modification of patient cells for re‐transplantation or direct in vivo gene targeting via advanced delivery methods.
Bahareh Farasati Far, Marziyeh Akbari, Mohammad Amin Habibi, Morteza Katavand, Sherko Nasseri   +4 more
wiley   +1 more source

Comprehensive review on Fanconi anemia: insights into DNA interstrand cross-links, repair pathways, and associated tumors. [PDF]

Orphanet J Rare Dis
Fang C, Zhu Z, Cao J, Huang J, Xu Y.
europepmc   +1 more source

Crystal structure and biophysical characterisation of the enterococcal foldase PpiC, a cross‐opsonic antigen against gram‐positive nosocomial pathogens

The FEBS Journal, EarlyView.
PpiC is an enterococcal lipoprotein endowed with both Peptidyl‐prolyl cis‐trans isomerase (PPIase) and foldase activities. It is a potential target for novel antimicrobials and a promising vaccine antigen. We determined the crystal structure of the enzyme, showing that PpiC adopts a dimeric organisation embedding two catalytic parvulin‐type PPIase ...
Valeria Napolitano, Eliza Kramarska, Ornella Ghilardi, Felipe Romero‐Saavedra, Pompea Del Vecchio, Flavia Squeglia, Johannes Huebner, Rita Berisio   +7 more
wiley   +1 more source

Protocol to generate genetically engineered organoid-initiated mouse models of esophageal cancer. [PDF]

STAR Protoc
Wang J, Du J, Luo X, Guo L, Li X, Dong Z, Lu Z, Wan X, Wang L, Liu H, Li H, Tan P, Ji Y, Li Y, Li Y, Yang Y, Yuan Y, Chen L, Hu B, Liu Y, Na F, Chen C.   +21 more
europepmc   +1 more source

Emerging roles for integrated stress response signaling in homeostasis

The FEBS Journal, EarlyView.
Integrated stress response (ISR), an evolutionarily conserved eukaryotic stress‐adaptive program in eukaryotes, has also been implicated in homeostatic functions. This review covers a broad body of literature and presents several homeostatic functions of ISR in the absence of stress: (a) developmental processes (morphogenesis, differentiation, aging), (
Shyama Nandakumar, Lydia Grmai, Deepika Vasudevan   +2 more
wiley   +1 more source

Benchmark center volume and regional disparity in living donor liver transplantation. [PDF]

Hepatobiliary Surg Nutr
Vella I, di Francesco F, Petri SL, Pagano D, Accardo C, Mamone G, Calamia S, Gruttadauria S.   +7 more
europepmc   +1 more source