Results 141 to 150 of about 1,297,973 (324)

Ex vivo perfusion, arteriography, and autotransplantation procedures for kidney salvage [PDF]

, 1973
Three kidneys with arterial lesions that would have been difficult or impossible to repair by standard vascular reconstruction were removed, perfused by the Belzer technique, and returned to host after partial or complete autotransplantation.
Anderson, JT, Corman, JL, Halgrimson, CG, Popovtzer, M, Stables, DP, Starzl, TE, Taubman, J   +6 more
core  

Human Induced Pluripotent Stem Cell-Derived Podocytes Mature into Vascularized Glomeruli upon Experimental Transplantation.

Journal of the American Society of Nephrology, 2016
Sazia Sharmin, Atsuhiro Taguchi, Yusuke Kaku, Yasuhiro Yoshimura, Tomoko Ohmori, Tetsushi Sakuma, M. Mukoyama, Takashi Yamamoto, H. Kurihara, R. Nishinakamura   +9 more
semanticscholar   +1 more source

Simultaneous Ex Situ Normothermic Perfusion of Paired Kidneys in Pigs

Artificial Organs, EarlyView.
This pig model of simultaneous perfusion of paired kidneys in normothermia suggests that intra‐individual variation is relatively low, enabling one kidney to be employed as a reliable comparator of the other kidney for assessing treatments before kidney transplantation.
Margaux Navez, Nicholas Gilbo, Morgan Vandermeulen, Tiago Pinto Coelho, Pauline Erpicum, Marc Gilbert Lagny, Clarisse Malisoux, Claire Guarin, Gabriel Thierry, Pierre Delanaye, Etienne Cavalier, François Jouret, Olivier Detry   +12 more
wiley   +1 more source

Emerging role of G protein‐coupled receptor class C group 5 member D‐directed immunotherapy in multiple myeloma: Advances, resistance and combination strategies

British Journal of Haematology, EarlyView.
Summary Multiple myeloma (MM) is a clonal malignancy of plasma cells characterized by frequent relapse and therapeutic resistance. G protein‐coupled receptor class C group 5 member D (GPRC5D) has emerged as a promising immunotherapeutic target due to its high and selective expression in MM cells and minimal presence in normal tissues.
Xueting Wang, Yushan Cui, Yaomei Wang, Baijun Fang   +3 more
wiley   +1 more source

Molecular biology of the mouse Q region [PDF]

, 1987
A. Eastman O'Neill, A. Winoto, A.-M. Lew, A.L. Mellor, A.L. Mellor, A.L. Mellor, C. Jaulin, C.G. Miyada, D. Cosman, D. Cosman, D. Stephan, D.A. Fisher, D.H. Schulze, D.S. Straus, E.H. Weiss, E.H. Weiss, E.H. Weiss, Elisabeth H. Weiss, F. Bregegere, I. Stroynowski, J. Geliebter, J. Klein, J. Michaelson, J. Stroynowski, J.H. Rogers, J.H. Rogers, J.J. Devlin, J.J. Devlin, J.L. Lalanne, J.L. Lalanne, L. Flaherty, L. Flaherty, L.R. Pease, M. Kress, M. Steinmetz, M. Steinmetz, R.A. Flavell, R.A. Flavell, R.S. Goodenow, S.G. Nathenson, W.L. Maloy, Y. Obata   +41 more
core   +1 more source

The BH3‐only protein NOXA is essential for apoptosis induction by BH3‐mimetics targeting BCL2 or BCL‐XL in DLBCL

British Journal of Haematology, EarlyView.
Summary BCL2 inhibitors (BCL2i) have transformed the management of chronic lymphocytic leukaemia (CLL), but their use in more aggressive B‐cell malignancies such as diffuse large B‐Cell lymphoma (DLBCL) is complicated by the more heterogeneous nature of the disease.
Nahide Yildirim, Marius Anders, Victoria M. Smith, Sandrine Jayne, Moritz Assmann, Rebekah Jukes‐Jones, Martin J. S. Dyer, Meike Vogler   +7 more
wiley   +1 more source

Confronting medical grifting: Fraudulent and unproven products and interventions in apheresis, transfusion and biotherapies

British Journal of Haematology, EarlyView.
A basic overview of medical grifting for haematologists with practical guidance in identification and tips for management. Summary Medical scams or grifting has long been a societal issue, though in recent years, the problem has become increasingly mainstream, especially as it relates to transfusion medicine, apheresis and biotherapies.
Brian D. Adkins, Sheharyar Raza, Victoria Costa, Elizabeth S. Allen, Laura D. Stephens, Jennifer S. Woo, Garrett S. Booth, Jeremy W. Jacobs   +7 more
wiley   +1 more source

Re‐make, re‐model: evolution and development of vertebrate cranial lateral lines

Biological Reviews, EarlyView.
ABSTRACT Lateral lines are placodally derived mechanosensory systems on the heads and trunks of many aquatic vertebrates. There is evidence of lateral lines in the earliest known vertebrate fossils, and they exist in organisms with widely different craniofacial morphologies – including the presence or absence of jaws, external or internal nostrils, and
Vishruth Venkataraman, Marco Lopez, Victoria E. Prince, Michael I. Coates   +3 more
wiley   +1 more source

IMPDH and GTP Metabolism in Cancer: Mechanisms, Regulation, and Translational Scope

Cancer Science, EarlyView.
This review provides a systematic summary of the current understanding of IMPDH biology, emphasizing its complex regulation and therapeutic relevance in cancer. We will outline key unresolved questions, including isozyme‐specific roles and mechanisms for escaping regulations, and propose mechanistic and translational strategies to design IMPDH‐targeted
Aki Ogawa‐Iio, Koh Takeuchi, Keita Shigemi, Michelle Jane Genoveso, Hiroaki Niitsu, Iemasa Koh, Yusei Ota, Keita Yamane, Takao Hinoi, Natsuki Osaka, Masashi Oshima, Tomohiro Ishikawa, Tomoyuki Mizuno, Manabu Natsumeda, Kensuke Tateishi, Rintaro Hashizume, Satoru Osuka, Susumu Goyama, Tomoharu Yasuda, Toshiya Senda, Atsuo T. Sasaki   +20 more
wiley   +1 more source

Organoid Models to Study Human Infectious Diseases

Cell Proliferation, EarlyView.
Our manuscript reviews the role of organoids as models for studying human infectious diseases, highlighting their irreplaceable contributions to drug testing and vaccine development for significant infectious diseases including HIV, ZIKV, SARS‐CoV‐2 and MPXV.
Sijing Zhu, Dan Chen, Xinzhi Yang, Liuliu Yang, Yuling Han   +4 more
wiley   +1 more source