Results 161 to 170 of about 73,189 (295)
Research Advances of the Autophagy‐Regulated Radiosensitivity
Autophagy plays a dual role in regulating cellular radiosensitivity in radiotherapy (RT). We discuss the mechanisms by which autophagy promotes survival and growthsuppression by modulating radiosensitivity. It also outlines some frontier autophagy‐targeted radiotherapies. ABSTRACT Autophagy is an evolutionarily conserved process of cell self‐catabolism
Hanyue Liu+7 more
wiley +1 more source
Patient Blood Management in pediatric and adolescent bone marrow donors: results from an Italian survey. [PDF]
Fante CD+5 more
europepmc +1 more source
Macrophage Efferocytosis as a Therapeutic Strategy in Intervertebral Disc Degeneration
Macrophages, integral to degenerated intervertebral discs, play a critical role in disc degeneration. By performing efferocytosis, they clear apoptotic cells. This article explores the process of efferocytosis, its molecular mechanisms, potential therapeutic implications for intervertebral disc degeneration and future strategies for targeted treatments.
Shijie Chen+9 more
wiley +1 more source
Preliminary high-dose irradiation of the recipient and associated damage of bone marrow stromal compartment enables bone marrow stroma transplantation. [PDF]
Bigildeev A+5 more
europepmc +1 more source
YKT6 Is Essential for Male Fertility by Promoting Meiosis Progression During Spermatogenesis of Mice
Specifically ablating Ykt6 in pre‐meiotic germ cells and meiotic spermatocytes leads to complete sterility and meiotic arrest in conditional knockout male mice. YTK6 is required for stabilising intercellular bridges between spermatocytes due to its key role in maintaining protein homeostasis and vesicular transport‐dependent functions in spermatocytes,
Jie Cen+8 more
wiley +1 more source
Mitochondrial Transplantation/Transfer: Promising Therapeutic Strategies for Spinal Cord Injury. [PDF]
Xiong X+8 more
europepmc +1 more source
History of organ transplantation via the two-way paradigm [PDF]
Demetris, AJ, Murase, N, Starzl, TE
core
CRISPR‐Cas systems offer transformative genome editing capabilities for precise manipulation of cellular genes. This enables two main therapeutic avenues: ex vivo modification of patient cells for re‐transplantation or direct in vivo gene targeting via advanced delivery methods.
Bahareh Farasati Far+4 more
wiley +1 more source