Results 171 to 180 of about 1,296,795 (347)

Transplantation tolerance, microchimerism, and the two-way paradigm [PDF]

, 1998
Demetris, AJ, Starzl, TE
core   +1 more source

The Biomaterial and Blood Clot Complex: A Crucial Early Environment for Osteo‐Coagulo‐Immunomodulation and the Advancement of Bone Biomaterials

Small Structures, EarlyView.
Various properties of bone biomaterials can modulate components of the blood clot (including the fibrin network, red blood cells, platelets, and the complement system) in vivo implantation, leading to the formation of a biomaterial–blood clot complex (BBCC) significantly impacting subsequent osteoimmunomodulation.
Zongpu Han, Jieyun Xu, Xinyu Guo, Lingyu Liang, Linjun Zhang, Yu Su, Wendong Gao, Qingming Tang, Lili Chen, Zhuofan Chen, Yin Xiao, Zetao Chen   +11 more
wiley   +1 more source

Surgery: Art or science? Birth of organ transplantation [PDF]

, 1998
Billingham, Billingham, Burnet, Calne, Carrel, Daston, Dausset, Dempster, Dubost, Gibson, Groth, Hamburger, Hamburger, Hau, Holman, Holton, Jaboulay, Küss, Küss, küss, Kœstler, Lawrence, Mathé, Medawar, Merrill, Merrill, Michon, Mitchison, Morgan, Murray, Servelle, Starzl, Starzl, Starzl, Starzl, T.E. Starzl, Unger, Voronoy Yu   +37 more
core   +1 more source

Unveiling the complex extra‐oral colonization pathways and pathogenic mechanisms of Fusobacterium nucleatum, a heterogeneous oral pathogen

VIEW, EarlyView.
We summarize the taxonomic characteristics, capabilities to adhere to and invade host cells, extra‐oral ectopic colonization pathways, and major pathogenic mechanisms of Fusobacterium nucleatum, and explore the regulation of F. nucleatum’s pathogenesis, aiming to provide references and assistance for the development of clinical interventions and future
Zhiwei Guan, Houbao Qi, Qiang Feng
wiley   +1 more source

CRISPR/Cas9‐edited tumor‐associated immune cells in cancer immunotherapy

VIEW, EarlyView.
Abstract Immuno‐oncology represents an emerging field that has significantly transformed tumor therapeutics, with immune cells serving as the cellular foundations of cancer immunotherapy. Due to its high efficiency and sensitivity, CRISPR/Cas9 genome editing is a highly promising technique for precise and rapid gene modification.
Yuhui Ma, Junxin Chen, Yuan Du, Zhihao Cao, Weizhi Ji, Yuyu Niu, Zebin Yang   +6 more
wiley   +1 more source

Aprotinin in orthotopic liver transplantation [PDF]

, 1993
Bechstein, W. O., Blumhardt, G., Gerlach, H., Himmelreich, G., Jochum, Marianne, Keck, H., Neuhaus, P., Riess, H., Roissaint, R.   +8 more
core   +1 more source

ConTrans: Weak-to-Strong Alignment Engineering via Concept Transplantation [PDF]

arXiv
Ensuring large language models (LLM) behave consistently with human goals, values, and intentions is crucial for their safety but yet computationally expensive. To reduce the computational cost of alignment training of LLMs, especially for those with a huge number of parameters, and to reutilize learned value alignment, we propose ConTrans, a novel ...
arxiv  

The SUV39 Family of H3K9 Methyltransferases in Skeletal Muscle Stem Cells

FASEB BioAdvances, EarlyView.
The SUV39 family members are well known for methylating the Lysine 9 of the histone H3 (H3K9) in order to compact the chromatin and contributing to gene repression. We describe their active role in proliferating and differentiating muscle stem cells, how they prevent from inflammation and fibrosis during muscle regeneration and the future avenues ...
Pauline Garcia, Slimane Ait‐Si‐Ali, Fabien Le Grand   +2 more
wiley   +1 more source

Evaluation of the conservation value and conservation difficulty of local populations of the rare plant Viola raddeana based on genetic diversity and gene expression information using next‐generation sequencers

Plant Species Biology, EarlyView.
We evaluate the conservation difficulty and genetic diversity of populations of the rare plant Viola raddeana at five sites based on harmful gene accumulation and gene duplication data gathered using RNA‐seq. Moreover, we evaluate the genetic diversity and structure of these populations using single‐nucleotide polymorphism (SNP) data acquired using ...
Hiroaki Shiraishi, Yoshihisa Suyama, Takashi Makino, Shun K. Hirota, Kazuo Obata, Jung‐Hyun Lee, Hyeok Jae Choi, Yoshihiko Tsumura   +7 more
wiley   +1 more source

The use of deidentified organ donor testes for research

Andrology, EarlyView.
Abstract Our knowledge of testis development and function mainly comes from research using mammalian model organisms, primarily the mouse. However, there are integral differences between men and other mammalian species regarding cellular composition and expression profiles during fetal and post‐natal testis development and in the mature testis ...
Marina V. Pryzhkova, Marnie W. Skinner, Juliana I. Candelaria, Stephen R. Wellard, Philip W. Jordan   +4 more
wiley   +1 more source