Results 181 to 190 of about 1,296,795 (347)

The mystique of organ transplantation [PDF]

open access: yes, 2005
Bach   +48 more
core   +1 more source

Simultaneous Ex Situ Normothermic Perfusion of Paired Kidneys in Pigs

open access: yesArtificial Organs, EarlyView.
This pig model of simultaneous perfusion of paired kidneys in normothermia suggests that intra‐individual variation is relatively low, enabling one kidney to be employed as a reliable comparator of the other kidney for assessing treatments before kidney transplantation.
Margaux Navez   +12 more
wiley   +1 more source

Genomic variant profiling in blast‐phase paediatric chronic myeloid leukaemia: Predisposing and driving alterations

open access: yesBritish Journal of Haematology, EarlyView.
To identify pathogenic somatic and germline gene variants associated with blast‐phase transformation and cancer predisposition in paediatric chronic myeloid leukaemia (CML), n = 19 patients with blast‐phase paediatric CML were analysed with whole genome and targeted panel sequencing and compared to n = 19 patients with chronic phase paediatric CML.
Yvonne Lisa Behrens   +22 more
wiley   +1 more source

Effect of ribonucleic acid perfusion on canine kidney and liver homograft survival. [PDF]

open access: yes, 1968
Brettschneider, L   +6 more
core  

Dimerisation of the VIP receptor VIPR2 is essential to its binding VIP and Gαi proteins, and to its functions in breast cancer cells

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Several G protein‐coupled receptors (GPCRs) are known to homodimerise. Dimeric GPCRs may have different properties from their monomers, but the molecular basis and functional significance of GPCR dimerisation remain largely unknown.
Satoshi Asano   +6 more
wiley   +1 more source

GGCT Inhibits Ferroptosis in PTC Cells by Upregulating p53 Through RPS15A

open access: yesCancer Science, EarlyView.
Our results showed that γ‐glutamine cyclotransferase (GGCT) knockdown in PTC cells inhibited GSH synthesis, promoted the malignant accumulation of malondialdehyde (MDA) and reactive oxygen species (ROS), and finally promoted cell ferroptosis. In vivo experiments showed that Pro‐GA, a specific inhibitor of GGCT, inhibited the subcutaneous tumorigenesis ...
Hui‐min Zhang   +9 more
wiley   +1 more source

Mesenchymal Stem Cell‐Derived Exosomes: A Promising Therapeutic Strategy for Age‐Related Diseases

open access: yesCell Proliferation, EarlyView.
Mechanisms of MSC‐Exos in the treatment of age‐related diseases. A Immunomodulatory and anti‐inflammatory, MSC‐Exos mediate immunomodulatory and anti‐inflammatory effects by regulating the polarisation of T cells and macrophages, promoting an anti‐inflammatory state while inhibiting pro‐inflammatory responses; B Suppression of oxidative stress, MSC ...
Bohua Wei   +5 more
wiley   +1 more source

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