Results 241 to 250 of about 1,297,973 (324)

Research Guideline Recommendations for Research on Stem Cells, Human Embryos, and Gene Editing. [PDF]

Cell Transplant
Var SR, Strell P, Shetty A, Roman A, Clark IH, Crane AT, Dunbar GL, Fink K, Grande AW, Parr AM, Rossignol J, Sanberg PR, Zhao LR, Zholudeva LV, Low WC, American Society for Neural Therapy and Repair Task Force.   +15 more
europepmc   +1 more source

Emerging role of HIC1 in prostate cancer progression and therapeutic response: A novel perspective

Journal of Cell Communication and Signaling, Volume 19, Issue 4, December 2025.
HIC1 inhibits AR expression to suppress the development of castration‐resistant prostate cancer through the IRS2/PI3K/AKT axis. Abstract Prostate cancer (PCa) is a leading cause of cancer‐related death in men, with its progression and treatment response being complex. The study focuses on the role of HIC1 (Hypermethylated in cancer 1) in PCa, revealing
Dun Xue, Long Tan, Fengshuai Yang, Xiaolan Tian, Qian Zuo, Xinghui Wu   +5 more
wiley   +1 more source

Phase II study of dual epigenetic targeting with chidamide and azacitidine in patients with high-risk acute myeloid leukemia after allo-HSCT. [PDF]

Clin Epigenetics
Wu YX, Wan CL, Tan KW, Zhang Y, Zhang YM, Zhang H, Wu DP, Chen SN, Wang Y, Ma X, Dai HP, Qian CS, Jiang SS, Bao HY, Hu XH, Li Z, Xue SL.   +16 more
europepmc   +1 more source

Metabolic studies following orthotopic liver transplantation [PDF]

, 1971
Starzl, TE
core  

Rapid‐Onset Therapeutic Effects of Delta Opioid Receptor Agonists on Depression‐Like Behaviors Induced by Chronic Social Defeat Stress

Neuropsychopharmacology Reports, Volume 45, Issue 4, December 2025.
Delta opioid receptor agonists improved social avoidance, depression, and anxiety‐like symptoms induced by chronic social defeat stress within 14 days of chronic administration. Furthermore, the therapeutic effects were observed earlier than with the existing antidepressant paroxetine (28 days).
Akihisa Tokuda, Yasuyuki Nagumo, Keita Kajino, Keita Iio, Katsuyasu Sakurai, Seiya Mizuno, Akiyoshi Saitoh, Tsuyoshi Saitoh, Hiroshi Nagase   +8 more
wiley   +1 more source

Screening for anti-Leishmania antibodies and Leishmania infections in kidney transplant recipients and donors from Brazil. [PDF]

Rev Inst Med Trop Sao Paulo
Johanson GH, Sanchez MCA, Souza RM, Celeste BJ, Valencia-Portillo RT, David Neto E, Pierrotti LC, Amato VS.   +7 more
europepmc   +1 more source

A Focus on Natural Autophagy Modulators as Potential Host‐Directed Weapons Against Emerging and Re‐Emerging Viruses

Medicinal Research Reviews, Volume 45, Issue 6, Page 1850-1882, November 2025.
ABSTRACT Autophagy is a highly conserved intracellular process involved in maintaining homeostasis and in the degradation of damaged organelles and external pathogens. Nature provides complex and varied reservoirs of scaffolds and chemical entities that may have a pivotal role in the search for new therapeutic leads.
Ilaria Cursaro, Sara Rossi, Stefania Butini, Sandra Gemma, Gabriele Carullo, Giuseppe Campiani   +5 more
wiley   +1 more source

Electroacupuncture Preconditioning Ameliorates the Ischemic Microenvironment to Improve Long-Term Potentiation in Chronic Cerebral Hypoperfusion Rats With MGE Neural Progenitor Transplantation. [PDF]

Neural Plast
Li D, Li J, Chen L, Wu Q, Lu M, Han X, Chen H.   +6 more
europepmc   +1 more source

Renal transplantation in the highly sensitized patient: The role of thoracic duct drainage, plasmapheresis, and staph A immunodepletion [PDF]

, 1990
Shapiro, R, Starzl, TE
core  

Transcriptome profiling of prostatic tumours from ENACT trial patients with or without enzalutamide

BJU International, Volume 136, Issue 5, Page 920-929, November 2025.
Objectives To evaluate the longitudinal transcriptomic changes that occurred over time in patients from the ENACT trial (ClinicalTrials.gov identifier: NCT02799745). ENACT evaluated patients with low‐ or intermediate‐risk prostate cancer, comparing the efficacy and safety of enzalutamide plus active surveillance (AS) to AS alone.
Nicole Handa, Neal D. Shore, Matthew R. Cooperberg, Elai Davicioni, Xin Zhao, Dina Elsouda, Yang Liu, James A. Proudfoot, Gaston Kuperman, David Russell, Kenneth K. Iwata, Edward M. Schaeffer, Ashley Ross   +12 more
wiley   +1 more source