Results 261 to 270 of about 1,296,795 (347)

Tailoring mRNA lipid nanoparticles for antifungal vaccines. [PDF]

PLoS Pathog
Li Y, Meagher RB, Lin X.
europepmc   +1 more source

Biopsy‐derived organoids in personalised early breast cancer care: Challenges of tumour purity and normal cell overgrowth cap their practical utility

International Journal of Cancer, Volume 156, Issue 11, Page 2200-2209, 1 June 2025.
What's new? Breast cancer patients often face relapse, sometimes years after initially successful therapy. It would therefore be highly desirable to develop a platform enabling routine assaying of individual efficacy of personalised therapies. Organoids have been proposed as a tool to serve this purpose, but the feasibility of their establishment from ...
Paul Schwerd‐Kleine, Roberto Würth, Tasneem Cheytan, Laura Michel, Verena Thewes, Ewgenija Gutjahr, Huriye Seker‐Cin, Daniel Kazdal, Sarah‐Jane Neuberth, Vera Thiel, Jonas Schwickert, Tim Vorberg, Jennifer Wischhusen, Albrecht Stenzinger, Marc Zapatka, Peter Lichter, Andreas Schneeweiss, Andreas Trumpp, Martin R. Sprick   +18 more
wiley   +1 more source

Should we Cryopreserve Allogenic Hematopoietic Stem Cell Grafts? [PDF]

In Vivo
Bembnista E, Stawicka P, Matuszak P, Łojko-Dankowska A, Dytfeld D, Matuszak M, Wache A, Kaźmierska K, Majewska E, Lewandowski K, Gil L.   +10 more
europepmc   +1 more source

Novel Strategies for Designing Climate‐Smart Crops to Ensure Sustainable Agriculture and Future Food Security

Journal of Sustainable Agriculture and Environment, Volume 4, Issue 2, June 2025.
As climate change gradually threatens crop yields, developing a sustainable and productive agricultural system is decisive. A multifaceted approach is needed to tackle climate change‐associated threats, integrating conventional agronomic practices with innovative management and mitigation strategies, such as breeding, sequence‐based and ...
Ali Raza, Tushar Khare, Xinyue Zhang, Md. Mezanur Rahman, Muzammil Hussain, Sarvajeet Singh Gill, Zhong‐Hua Chen, Meixue Zhou, Zhangli Hu, Rajeev K. Varshney   +9 more
wiley   +1 more source

Anti-stroke biologics: from recombinant proteins to stem cells and organoids. [PDF]

Stroke Vasc Neurol
Miao ZW, Wang Z, Zheng SL, Wang SN, Miao CY.   +4 more
europepmc   +1 more source

An optimised Bcl‐3 inhibitor for melanoma treatment

British Journal of Pharmacology, Volume 182, Issue 11, Page 2426-2446, June 2025.
Abstract Background and Purpose Malignant melanoma is the most lethal form of skin cancer, characterised by a poor survival rate. One of the key factors driving the aggressive growth of melanoma cells is the elevated expression of the proto‐oncogene Bcl‐3. This study aims to optimise, evaluate and characterise a second‐generation Bcl‐3 inhibitor, using
Karunakar Saamarthy, Renée Daams, Wondossen Sime, Cecilia Persson, Eduard Chygorin, Kristofer Ahlqvist, Susan Evans‐Axelsson, Daniel Strand, Ramin Massoumi   +8 more
wiley   +1 more source

Developing Mouse Models for Ovarian Tissue Transplantation and Xenotransplantation: A Review. [PDF]

Med Sci Monit
Liu FX, Lin Z, Huang KL.
europepmc   +1 more source

Progress in homotransplantation of the liver. [PDF]

, 1966
Marchioro, TL, Porter, KA, Starzl, TE
core  

GIGANTEA Is Required for Robust Circadian Rhythms in Wheat

Plant, Cell &Environment, Volume 48, Issue 6, Page 4492-4504, June 2025.
ABSTRACT GIGANTEA (GI) is a plant‐specific protein that functions in many physiological processes and signalling networks. In Arabidopsis, GI has a central role in circadian oscillators regulating the abundance of ZEITLUPE and TIMING OF CAB EXPRESSION 1 proteins and is essential for photoperiodic regulation of flowering.
Laura J. Taylor, Gareth Steed, Gabriela Pingarron‐Cardenas, Lukas Wittern, Matthew A. Hannah, Alex A. R. Webb   +5 more
wiley   +1 more source

Allogeneic Islet Transplantation: Chronicle of a Death Foretold? [PDF]

Transpl Int
Berney T, Thaunat O, Berishvili E.
europepmc   +1 more source