Results 271 to 280 of about 92,648 (319)

Should we Cryopreserve Allogenic Hematopoietic Stem Cell Grafts? [PDF]

In Vivo
Bembnista E, Stawicka P, Matuszak P, Łojko-Dankowska A, Dytfeld D, Matuszak M, Wache A, Kaźmierska K, Majewska E, Lewandowski K, Gil L.   +10 more
europepmc   +1 more source

The connected past and future of transplantation, with particular emphasis on the liver [PDF]

, 2004
Starzl, TE
core  

Biopsy‐derived organoids in personalised early breast cancer care: Challenges of tumour purity and normal cell overgrowth cap their practical utility

International Journal of Cancer, Volume 156, Issue 11, Page 2200-2209, 1 June 2025.
What's new? Breast cancer patients often face relapse, sometimes years after initially successful therapy. It would therefore be highly desirable to develop a platform enabling routine assaying of individual efficacy of personalised therapies. Organoids have been proposed as a tool to serve this purpose, but the feasibility of their establishment from ...
Paul Schwerd‐Kleine, Roberto Würth, Tasneem Cheytan, Laura Michel, Verena Thewes, Ewgenija Gutjahr, Huriye Seker‐Cin, Daniel Kazdal, Sarah‐Jane Neuberth, Vera Thiel, Jonas Schwickert, Tim Vorberg, Jennifer Wischhusen, Albrecht Stenzinger, Marc Zapatka, Peter Lichter, Andreas Schneeweiss, Andreas Trumpp, Martin R. Sprick   +18 more
wiley   +1 more source

Anti-stroke biologics: from recombinant proteins to stem cells and organoids. [PDF]

Stroke Vasc Neurol
Miao ZW, Wang Z, Zheng SL, Wang SN, Miao CY.   +4 more
europepmc   +1 more source

PRMT5 Promotes Pancreatic Cancer Tumorigenesis via Positive PRMT5/C‐Myc Feedback Loop

MedComm, Volume 6, Issue 6, June 2025.
By forming a positive feedback loop with c‐Myc, PRMT5 promoted the pancreatic cancer tumorigenesis. Inactivation of PRMT5 with small molecular inhibitors led to suppressed proliferation, colony formation, enhanced apoptosis, and cell cycle arrest. Targeting PRMT5 exhibited promising therapeutic effect for pancreatic cancer . ABSTRACT The oncogenic role
Fan Yang, Ping Song, Zhaofeng Xiao, Renyi Su, Xin Fang, Yichao Wu, Xiao Xu, Kai Wang   +7 more
wiley   +1 more source

Progress toward the challenging goal of HDR-based gene editing for hyper-IgM syndrome. [PDF]

Mol Ther Methods Clin Dev
Bazzo Catto LF, Dunbar CE.
europepmc   +1 more source

Targeting the Enhanced Sensitivity of Radiotherapy in Cancer: Mechanisms, Applications, and Challenges

MedComm, Volume 6, Issue 6, June 2025.
In this review, we first introduced the current application scenarios for radiotherapy in tumor treatment, the molecular mechanisms underlying anticancer effects of radiotherapy in treatment of cancer, and the side‐effects of radiotherapy. Second, we pay attention to discuss the main types of radiosensitizers and their latest applications and ...
Yuanyuan Zhao, Fangqin Tan, Jiajia Zhao, Shuchang Zhou, Yao Luo, Chen Gong   +5 more
wiley   +1 more source

Vaccines for preventing infections in adults with solid tumours. [PDF]

Cochrane Database Syst Rev
Hirsch C, Zorger AM, Baumann M, Park YS, Bröckelmann PJ, Mellinghoff S, Monsef I, Skoetz N, Kreuzberger N.   +8 more
europepmc   +1 more source

Genome editing in spinocerebellar ataxia type 3 cells improves Golgi apparatus structure. [PDF]

Sci Rep
Wang Y, Cheng Y, Sun H, Wang Z, Chen N, Shi C, Liu H, Yang J, Xu Y.   +8 more
europepmc   +1 more source

Successful BRCA2 Mutation Detection via Tissue-Based Gene Panel Testing in Post-bone Marrow Transplant Breast Cancer: Implications for Precision Medicine. [PDF]

Cureus
Takeuchi C, Imanishi S, Tanaka N, Kittaka N.   +3 more
europepmc   +1 more source