Results 211 to 220 of about 1,841,497 (285)

Engineered Tissue Models to Decode Host–Microbiota Interactions

Advanced Science, EarlyView.
Host–Microbiota interactions in the human body. Created in BioRender. Ghezzi, C. (2025) https://BioRender.com/ihivskg. Abstract A mutualistic co‐evolution exists between the host and its associated microbiota in the human body. Bacteria establish ecological niches in various tissues of the body, locally influencing their physiology and functions, but ...
Miryam Adelfio, Grace E. Callen, Xuesong He, Bruce J. Paster, Hatice Hasturk, Chiara E. Ghezzi   +5 more
wiley   +1 more source

Chimerism and immunological tolerance in solid organ transplantation. [PDF]

Semin Immunopathol
Ohm B, Giannou AD, Harriman D, Oh J, Jungraithmayr W, Zazara DE.   +5 more
europepmc   +1 more source

Bioengineered Tumor‐Derived Extracellular Vehicles Suppressed Colorectal Cancer Liver Metastasis and Bevacizumab Resistance

Advanced Science, EarlyView.
The upregulated CCL24 in CRC liver metastasis promotes the formation of inflammatory tumor‐associated fibroblast subsets and induces resistance to bevacizumab therapy. Downregulation of CCL24 significantly increased sensitivity to antiangiogenic therapy in CRC mouse model. Hence, a novel therapeutic target is identified for patients with CRC with liver
Junjiang Wang, Chunsheng Liu, Ping Wang, Zhiyuan Liu, Weixian Hu, Zejian Lv, Chengzhi Huang, Xueqing Yao   +7 more
wiley   +1 more source

Precision Monitoring of Immunosuppressive Agent Concentrations in Cardiac Tissue of Pediatric Heart Transplant Recipients. [PDF]

Pediatr Transplant
Hashimoto K, Kimura N, Narita J, Ishii R, Hirose M, Hayashi K, Nishino H, Ueyama A, Ueda K, Yoshihara C, Kitabatake Y, Nagai R, Aizawa K, Ishida H.   +13 more
europepmc   +1 more source

KK2DP7 Stimulates CD11b+ Cell Populations in the Spleen to Elicit Trained Immunity for Anti‐Tumor Therapy

Advanced Science, EarlyView.
This study introduces KK2DP7, a dendrimer‐structured peptide adjuvant, as a tool to decode trained immunity's role in antitumor therapy. Splenic CD11b+ cells mediate tumor suppression via TLR2‐IRF7 activation and epigenetic reprogramming, validated by adoptive transfer experiments.
Rui Zhang, Lin Tang, Yusi Wang, Xuejing Zhou, Zhenyu Ding, Li Yang   +5 more
wiley   +1 more source

Association between the Stanford Integrated Psychosocial Assessment for Transplant and 1-year medication nonadherence after living kidney transplantation. [PDF]

PCN Rep
Takano K, Kobayashi S, Oshibuchi H, Tsutsui J, Ito S, Kamba R, Akaho R, Nishimura K.   +7 more
europepmc   +1 more source

Fish Swim Bladder‐Derived ECM Hydrogels Effectively Treat Myocardial Ischemic Injury through Immunomodulation and Angiogenesis

Advanced Science, EarlyView.
A unique hydrogel based on extracellular matrix from fish swim bladder, which is suitable for transcatheter delivery and possesses remarkable reparative capabilities for treating heart failure, is developed. It emerges as a multi‐effect factor profoundly influencing inflammation regulation, angiogenesis, and myocardial metabolism.
Yulong Fu, Canran Gao, Hailing Zhang, Jing Liu, Boxuan Li, Wei Chen, Xiuping Chen, Xue Lin, Ligang Fang, Zhihong Wang   +9 more
wiley   +1 more source

Novel Electroactive Therapeutic Platforms for Cardiac Arrhythmia Management

Advanced Science, EarlyView.
Electroactive platforms offer promising applications in cardiac arrhythmia. Based on their energy sources and mechanisms, electroactive platforms are categorized into i) direct electrical stimulation, ii) self‐powered electroactive systems, iii) physical stimuli‐mediated electroactive systems, and iv) conductive systems, and their applications in ...
Juwei Yang, Longfei Li, Yiran Hu, Zhou Li, Wei Hua   +4 more
wiley   +1 more source

The donation-transplantation process and corneal graft failure: A case-control study. [PDF]

PLoS One
Pereira Cruz GK, Ferreira Júnior MA, Pereira Santos VE, Vitor AF, Pereira Frota O, Ferraz Teston E, Machado Mota F, Gonçalves Zulin ME, Moura Maidana G, Lima Meza L, Dias Abes B, Dias M.   +11 more
europepmc   +1 more source