Results 271 to 280 of about 2,284,885 (351)

RENAL TRANSPLANTATION

The Lancet, 1969
openaire   +4 more sources

Genetic Ablation and Multi‐Omics Profiling Reveal CEP55 as a Key Driver of Tumorigenesis in Diverse Cancer Models

Advanced Science, EarlyView.
Genetic ablation of Cep55 in Pten‐deficient mouse models delays tumorigenesis. Integrated multi‐omics analyses (proteomics, phosphoproteomics, and spatial transcriptomics) reveal that CEP55 regulates oncogenic signaling (RAS/ERK, PI3K/AKT), integrin/FAK‐mediated adhesion, extracellular matrix (ECM) remodeling, and endocytosis.
Behnam Rashidieh, Yuanhao Yang, Amanda Louise Bain, Phillip Theron, Catharina Vosloo, Sahar Keshvari, Parinaz Ahangar, Brydie Bowden, Simon M. Tria, Ben B. Wang, Sandra Isenmann, Nicholas J. Westra van Holthe, Zherui Xiong, Hani Vu, Sowmya Sharma, Asmerom Sengal, J. Alejandro Lopez, John Finnie, Antonella Papa, Pascal H.G. Duijf, Quan Nguyen, Pirjo M. Apaja, Kum Kum Khanna   +22 more
wiley   +1 more source

PDCD1 SNPs and alloimmune transplant outcomes: mechanistic basis and human evidence across solid organ transplantation and allogeneic hematopoietic stem cell transplantation. [PDF]

Biochem Biophys Rep
Rabet H, Hosseini SM.
europepmc   +1 more source

RGS16 Aggravates Hepatic Ischemia‐Reperfusion Injury via Hepatocyte‐Intrinsic Apoptosis/Inflammation & Neutrophil Recruitment/NETosis

Advanced Science, EarlyView.
RGS16 competitively interferes with the YTHDF3–PAN3 complex to prevent CXCL1 mRNA decay during hepatic ischemia‐reperfusion injury. Stabilized CXCL1 strengthens hepatocyte injury, neutrophil recruitment, and NET‐associated inflammation, uncovering how stress‐induced RGS16 converts post‐transcriptional regulation into immune‐mediated liver damage ...
Xinglong Li, Zhanzhi Meng, Hongjun Yu, Yongliang Hua, Zihao Li, Bing Yin, Baolin Qian, Zhongyu Li, Yongzhi Zhou, Zhigang Feng, Shounan Lu, Shanjia Ke, Miaoyu Bai, Yao Fu, Wei Tang, Natalia V. Belosludtseva, Yong Ma   +16 more
wiley   +1 more source

3D bioprinted human vascular organoid sheets promote functional ischemic repair and exhibit adaptive in vivo remodeling. [PDF]

BMC Med
Fu X, Yan L, Chen Z, Dou B, Zhou D, Zhou X, Qu K, Gao C, Wang P, Zhang F, Zou Z, Wang T, Li G, Ouyang L, Na J.   +14 more
europepmc   +1 more source

Ferroptosis blockade: beyond preservation to active graft therapy. [PDF]

Signal Transduct Target Ther
Xing C, Oniscu GC, Lauschke VM.
europepmc   +1 more source

Recurrent and De Novo Cirrhosis After Liver Transplantation. [PDF]

Portal Hypertens Cirrhosis
Rao AK, Rockey DC.
europepmc   +1 more source

Transmission of Anellovirus From Kidney-Donor to Pediatric Recipient: An Exploratory Study. [PDF]

Pediatr Transplant
Klomp LS, Burggraaff MGJM, Bakker M, Molier M, Timmerman AL, Deijs M, Feltkamp M, van der Hoek L, Bouts AHM.   +8 more
europepmc   +1 more source