Results 21 to 30 of about 2,284,885 (351)

HLA-DQ-Specific Recombinant Human Monoclonal Antibodies Allow for In-Depth Analysis of HLA-DQ Epitopes

Frontiers in Immunology, 2022
HLA-DQ donor-specific antibodies (DSA) are the most prevalent type of DSA after renal transplantation and have been associated with eplet mismatches between donor and recipient HLA. Eplets are theoretically defined configurations of surface exposed amino
Suzanne Bezstarosti, Suzanne Bezstarosti, Cynthia S. M. Kramer, Marry E. I. Franke-van Dijk, Manon Vergunst, Kim H. Bakker, Merve Uyar-Mercankaya, Rico Buchli, Dave L. Roelen, Johan W. de Fijter, Frans H. J. Claas, Frans H. J. Claas, Sebastiaan Heidt, Sebastiaan Heidt   +13 more
doaj   +1 more source

Graft-versus-host disease after simultaneous pancreas-kidney transplantation [PDF]

, 2020
Graft-versus-host disease (GVHD) is rare complication after simultaneous pancreas-kidney transplantation (SPK). Here, we present a rare case of GVHD that developed in a SPK recipient.
이재근, 이주한, 김명수, 김순일, 허규하, 주동진   +5 more
core   +1 more source

Microbiota as Predictor of Mortality in Allogeneic Hematopoietic-Cell Transplantation

New England Journal of Medicine, 2020
BACKGROUND Relationships between microbiota composition and clinical outcomes after allogeneic hematopoietic-cell transplantation have been described in single-center studies.
J. Peled, A. Gomes, S. Devlin, E. Littmann, Y. Taur, A. Sung, D. Weber, D. Hashimoto, A. E. Slingerland, J. Slingerland, M. Maloy, A. Clurman, C. Stein-Thoeringer, K. Markey, M. Docampo, M. Burgos da Silva, N. Khan, A. Gessner, J. Messina, K. Romero, M. Lew, A. Bush, L. Bohannon, Daniel G. Brereton, E. Fontana, L. Amoretti, R. Wright, G. Armijo, Y. Shono, Miriam Sánchez-Escamilla, Nerea Castillo-Flores, Ana Alarcon Tomas, R. Lin, Lucrecia Yáñez San Segundo, G. Shah, C. Cho, M. Scordo, Ioannis Politikos, K. Hayasaka, Y. Hasegawa, B. Gyurkocza, D. Ponce, J. Barker, M. Perales, S. Giralt, R. Jenq, T. Teshima, Nelson J. Chao, E. Holler, J. Xavier, E. Pamer, M. R. van den Brink   +51 more
semanticscholar   +1 more source

Regenerative medicine applications: An overview of clinical trials

Frontiers in Bioengineering and Biotechnology, 2022
Insights into the use of cellular therapeutics, extracellular vesicles (EVs), and tissue engineering strategies for regenerative medicine applications are continually emerging with a focus on personalized, patient-specific treatments.
Astgik Petrosyan, Paulo N. Martins, Kim Solez, Basak E. Uygun, Vijay S. Gorantla, Giuseppe Orlando   +5 more
doaj   +1 more source

Advances in dendritic cell targeting nano-delivery systems for induction of immune tolerance

Frontiers in Bioengineering and Biotechnology, 2023
Dendritic cells (DCs) are the major specialized antigen-presenting cells (APCs), play a key role in initiating the body’s immune response, maintain the balance of immunity.
Guojiao Lin, Guojiao Lin, Jialiang Wang, Jialiang Wang, Yong-Guang Yang, Yong-Guang Yang, Yong-Guang Yang, Yuning Zhang, Yuning Zhang, Tianmeng Sun, Tianmeng Sun, Tianmeng Sun, Tianmeng Sun   +12 more
doaj   +1 more source

Application of Mesenchymal Stem Cells During Machine Perfusion: An Emerging Novel Strategy for Organ Preservation

Frontiers in Immunology, 2021
Although solid organ transplantation remains the definitive management for patients with end-stage organ failure, this ultimate treatment has been limited by the number of acceptable donor organs.
Jiale Li, Qinbao Peng, Ronghua Yang, Kunsheng Li, Peng Zhu, Yufeng Zhu, Pengyu Zhou, Gábor Szabó, Gábor Szabó, Shaoyi Zheng   +9 more
doaj   +1 more source

The Immunological Basis of Liver Allograft Rejection

Frontiers in Immunology, 2020
Liver allograft rejection remains a significant cause of morbidity and graft failure in liver transplant recipients. Rejection is caused by the recognition of non-self donor alloantigens by recipient T-cells.
Vincenzo Ronca, Vincenzo Ronca, Vincenzo Ronca, Grace Wootton, Chiara Milani, Owen Cain   +5 more
doaj   +1 more source

Reconstruction of the trachea and carina: Surgical reconstruction, autologous tissue transplantation, allograft transplantation, and bioengineering

Thoracic Cancer, 2022
There have been significant advancements in medical techniques in the present epoch, with the emergence of some novel operative substitutes. However, the treatment of tracheal defects still faces tremendous challenges and there is, as yet, no consensus ...
Jianghao Ren, Yuanyuan Xu, Guo Zhiyi, Ting Ren, Jiangbin Ren, Kan Wang, Yiqing Luo, Mingyang Zhu, Qiang Tan   +8 more
doaj   +1 more source

Bortezomib, thalidomide, and dexamethasone with or without daratumumab before and after autologous stem-cell transplantation for newly diagnosed multiple myeloma (CASSIOPEIA): a randomised, open-label, phase 3 study.

The Lancet, 2019
BACKGROUND Bortezomib, thalidomide, and dexamethasone (VTd) plus autologous stem-cell transplantation is standard treatment in Europe for transplant-eligible patients with newly diagnosed multiple myeloma. We evaluated whether the addition of daratumumab
P. Moreau, M. Attal, C. Hulin, B. Arnulf, K. Belhadj, L. Benboubker, M. Béné, A. Broijl, H. Caillon, D. Caillot, J. Corre, M. Delforge, T. Dejoie, C. Doyen, T. Facon, C. Sonntag, J. Fontan, L. Garderet, Kon-Siong G. Jie, Lionel Karlin, F. Kuhnowski, J. Lambert, X. Leleu, P. Lenain, M. Macro, C. Mathiot, F. Orsini-Piocelle, A. Perrot, A. Stoppa, N. V. van de Donk, S. Wuillème, S. Zweegman, Brigitte Kolb, C. Touzeau, M. Roussel, M. Tiab, J. Marolleau, N. Meuleman, M. Vekemans, M. Westerman, S. Klein, M. Levin, J. Fermand, M. Escoffre-barbe, J. Eveillard, R. Garidi, T. Ahmadi, Sen H. Zhuang, Christopher Chiu, L. Pei, C. D. de Boer, E. Smith, W. Deraedt, T. Kampfenkel, J. Schecter, J. Vermeulen, H. Avet-Loiseau, P. Sonneveld   +57 more
semanticscholar   +1 more source

Nonalcoholic Steatohepatitis is the Most Rapidly Increasing Indication for Liver Transplantation in the United States.

Clinical Gastroenterology and Hepatology, 2020
BACKGROUND & AIMS The profile of chronic liver disease (CLD) in the United States has changed due to obesity trends and advances in treatment of viral hepatitis. We assessed liver transplant listing trends by CLD etiology.
Z. Younossi, M. Stepanova, J. Ong, G. Trimble, S. Alqahtani, I. Younossi, Aijaz Ahmed, A. Racila, L. Henry   +8 more
semanticscholar   +1 more source