Results 341 to 350 of about 2,959,960 (382)

RIG‐I‐Inducing Small Molecules Potently Inhibit HMA‐Resistant AML Through Igniting the Overloaded dsRNA Arsenal

Advanced Science, EarlyView.
This study reveals a novel mechanism of resistance to DNA hypomethylating agents (HMAs) in acute myeloid leukemia (AML), and identifies all‐trans retinoic acid (ATRA) and tamibarotene (TAM) as potent agents that overcome HMA resistance by reactivating the interferon anticancer immune response. The findings offer promising therapeutic strategies for HMA‐
Xueqin Chen, Jiaqi Wu, Yuntong Li, Jiayu Huang, Xiangqin Weng, Jiale Wu, Shujun Xiao, Huaxin Song, Zhengyuan Wang, Ni Yan, Fangfang Shi, Derun Zheng, Kai Tan, Hesong Zhang, Jingyi Cui, Wen Wu, Wei Wu, Sujiang Zhang, Min Lu   +18 more
wiley   +1 more source

Redefining the Immunobiology of Organ Transplantation for New Clinical Horizons. [PDF]

Scand J Immunol
Manjili MH.
europepmc   +1 more source

Correction to: Upcoming drug targets for kidney protective effects in chronic kidney disease. [PDF]

Nephrol Dial Transplant
europepmc   +1 more source

To transplant or not to transplant? [PDF]

Blood, 2005
Comment on Blade et al, page [3755][1] In this issue of Blood, Blade and colleagues report that HDT does not improve overall or event-free survival in patients responding to initial chemotherapy.
Nikhil C. Munshi, Kenneth C. Anderson
openaire   +1 more source

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Kidney Transplantation in the Obese Transplant Candidates: To Transplant or Not To Transplant?

Seminars in Dialysis, 2013
AbstractThe prevalence of obesity (body mass index ≥30 kg/m2) at the time of transplantation among kidney transplant recipients in the United States has doubled between 1987 and 2001 and continues to increase inexorably. Single‐center and large registry studies in kidney transplant recipients demonstrated that high body mass index (BMI) at transplant ...
Phuong-Chi T. Pham, Gabriel M. Danovitch, Phuong-Thu T. Pham   +2 more
openaire   +2 more sources

Transplantation

Pediatric Clinics of North America, 2016
Despite improvement in median life expectancy and overall health, some children with cystic fibrosis (CF) progress to end-stage lung or liver disease and become candidates for transplant. Transplants for children with CF hold the promise to extend and improve the quality of life, but barriers to successful long-term outcomes include shortage of ...
Albert, Faro, Alexander, Weymann
openaire   +2 more sources

Survival in adult lung transplantation: where are we in 2020?

Current Opinion in Organ Transplantation, 2020
PURPOSE OF REVIEW In this article, an overview of the survival after lung transplantation will be given, with a focus on factors affecting outcome and differences in survival determined by underlying disease.
S. Bos, R. Vos, D. Van raemdonck, G. Verleden   +3 more
semanticscholar   +1 more source

Vaccination of solid organ transplant candidates and recipients: Guidelines from the American society of transplantation infectious diseases community of practice

Clinical Transplantation, 2019
These updated guidelines of the AST IDCOP review vaccination of solid organ transplant candidates and recipients. General principles of vaccination as well as the use of specific vaccines in this population are discussed.
L. Danziger-Isakov, Deepali Kumar
semanticscholar   +1 more source