Results 71 to 80 of about 2,720,585 (409)
FEBS Letters, EarlyView.In vivo IL‐10 produced by tissue‐resident tolDC is involved in maintaining/inducing tolerance. Depending on the agent used for ex vivo tolDC generation, cells acquire common features but prime T cells towards anergy, FOXP3+ Tregs, or Tr1 cells according to the levels of IL‐10 produced. Ex vivo‐induced tolDC were administered to patients to re‐establish/
Konstantina Morali +3 more
wiley +1 more source
Revisiting Stem Cell-Based Clinical Trials for Ischemic Stroke
Frontiers in Aging Neuroscience, 2020 Stroke is the leading cause of serious long-term disability, significantly reducing mobility in almost half of the affected patients aged 65 years and older. There are currently no proven neurorestorative treatments for chronic stroke.
Joy Q. He +4 more
doaj +1 more source
Cardiovascular morbidity and mortality after kidney transplantation [PDF]
, 2014 Kidney transplantation is the optimal treatment for patients with end stage renal disease (ESRD) who would otherwise require dialysis. Patients with ESRD are at dramatically increased cardiovascular (CV) risk compared to the general population.
Jardine, Alan G. +2 more
core +1 more source
FoxO1 signaling in B cell malignancies and its therapeutic targeting
FEBS Letters, EarlyView.FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac +3 more
wiley +1 more source
Amniotic fluid-derived stem cells as an effective cell source for transplantation therapy in stroke
Brain Circulation, 2015 This review examines stem cells harvested from human amniotic fluid and considers their possible applications in regenerative medicine, specifically for stroke therapy.
Nicholas S Diaco +2 more
doaj +1 more source
IL-34 Actions on FOXP3+ Tregs and CD14+ Monocytes Control Human Graft Rejection
Frontiers in Immunology, 2020 Cytokines are major players regulating immune responses toward inflammatory and tolerogenic results. In organ and bone marrow transplantation, new reagents are needed to inhibit tissue destructive mechanisms and eventually induce immune tolerance without
Séverine Bézie +20 more
doaj +1 more source
Biomarkers in solid organ transplantation: establishing personalized transplantation medicine. [PDF]
, 2011 Technological advances in molecular and in silico research have enabled significant progress towards personalized transplantation medicine. It is now possible to conduct comprehensive biomarker development studies of transplant organ pathologies ...
Khatri, Purvesh +3 more
core +3 more sources
FEBS Letters, EarlyView.Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi +3 more
wiley +1 more source
Indian Journal of Transplantation, 2019 There is huge gap between patients requiring organ transplantation and the available organ donor pool. Various strategies are being pursued to expand the organ donor pool.
Dhanin Puthiyottil +11 more
doaj +1 more source
Organ and tissue transplantation [PDF]
, 1967 A report is delivered on the First International Congress of the Transplantation Society (Paris 1967). The recent interest in transplantation of organs is largely due to the technical advances in surgical procedures making it possible to replace organs ...
Cauchi, Maurice N.
core