Results 71 to 80 of about 1,899,797 (360)

Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu   +15 more
wiley   +1 more source

Quantitative Methods for Optimizing Patient Outcomes in Liver Transplantation [PDF]

open access: yesarXiv, 2023
Liver transplantation continues to be the gold standard for treating patients with end-stage liver diseases. However, despite the huge success of liver transplantation in improving patient outcomes, long term graft survival continues to be a major problem.
arxiv  

Chimerism after organ transplantation [PDF]

open access: yes, 1997
Recent evidence suggests that passenger leukocytes migrate after organ transplantation and produce persistent chimerism, which is essential for sustained survival of the allograft.
Demetris, AJ   +6 more
core   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

open access: yesMolecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit   +19 more
wiley   +1 more source

Therapeutic Potential of HUMSCs in Female Reproductive Aging

open access: yesFrontiers in Cell and Developmental Biology, 2021
With the development of regenerative medicine, stem cells are being considered more frequently for the treatment of reproductive aging. Human umbilical cord mesenchymal stem cells have been reported to improve the reserve function of aging ovaries ...
Qiaojuan Mei   +3 more
doaj   +1 more source

Treatment of hepatic epithelioid hemangioendothelioma with liver transplantation [PDF]

open access: yes, 1988
Ten patients received liver transplants for unresectable epithelioid hemangioendothelioma (EHE). At the time of transplantation, four patients had microscopic metastases to the hilar lymph nodes, and one of the four also had metastases to a rib.
Esquivel, CO   +7 more
core   +1 more source

Lung transplantation [PDF]

open access: yesEinstein (São Paulo), 2015
ABSTRACT Lung transplantation is a globally accepted treatment for some advanced lung diseases, giving the recipients longer survival and better quality of life. Since the first transplant successfully performed in 1983, more than 40 thousand transplants have been performed worldwide. Of these, about seven hundred were in Brazil.
Afonso Júnior, José Eduardo   +7 more
openaire   +5 more sources

Interplay of integrins and selectins in metastasis

open access: yesMolecular Oncology, EarlyView.
Here we review the role of integrins and their interplay with selectins in metastasis. The efficacy of integrin‐targeted therapies may be reduced in tumors where metastasis relies heavily on selectins. In certain tumors, integrins and selectins exhibit a synergistic interaction during intraperitoneal dissemination.
Diana Maltseva   +2 more
wiley   +1 more source

The principles of human organ transplantation procedure [PDF]

open access: yesZbornik Radova Pravnog Fakulteta u Nišu, 2019
The principles of human organ transplantation procedure must meet two requirements: the requirement of humanity, which all medical activities are based on, and the requirement for patients' protection and the preservation of human and personal rights of ...
Lazić Miroslav, Simonović Ivana
doaj  

Predicting tacrolimus exposure in kidney transplanted patients using machine learning [PDF]

open access: yesarXiv, 2022
Tacrolimus is one of the cornerstone immunosuppressive drugs in most transplantation centers worldwide following solid organ transplantation. Therapeutic drug monitoring of tacrolimus is necessary in order to avoid rejection of the transplanted organ or severe side effects.
arxiv  

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