Results 131 to 140 of about 18,682 (303)
Precision Radiation Oncology, EarlyView.Radiotherapy enhances CAR‐Tcell therapy by increasing antigenicity, improving trafficking, and reshaping the tumor microenvironment. Despite its dual effects, including potential immune suppression, understanding these mechanisms enables the development of strategies to maximize synergy in solid tumors.
Leran Qiu +4 more
wiley +1 more source
International Journal of Biological Sciences, 2011 Stem cells have the potential for self-renewal and differentiation. First stem cell cultures were derived 30 years ago from early developing mouse embryos. These are pluripotent embryonic stem (ES) cells.
Ni Hong, Zhendong Li, Yunhan Hong
doaj
Rheumatology &Autoimmunity, EarlyView.Graphical Abstract The evolving role of regulatory T cells in primary Sjögren's disease pathogenesis and the promise of Treg‐based therapies. Abstract Sjögren's disease (SjD) is a chronic systemic autoimmune disorder characterised by exocrine gland dysfunction and diverse systemic manifestations.
Gagan Urs +5 more
wiley +1 more source
Staging concept for aging management: Definition, mechanism, and coping strategies
VIEW, EarlyView.We divided the overall aging stage into “pre‐aging”, “aging compensation”, and “aging disability”. For each stage, we delineate the clinical presentations, biological phenomena, theoretical underpinnings, and key management priorities. Abstract Aging, as a gradual and largely irreversible biological process, characterized by declining organismal ...
Zhonghan Wang +6 more
wiley +1 more source
Integrative Zoology, EarlyView.18 days of predator odor exposure altered gut microbiota, increased anxiety‐like behaviors, and elevated hypothalamic–pituitary–adrenal axis activity in Brandt's voles, with males showing behavioral habituation and females remaining sensitive. Cecal microbiota transplantation experiments confirmed that only female recipients of microbiota from predator‐
Chen Gu +6 more
wiley +1 more source
Transplantation Milestones: Viewed With One-and Two-Way Paradigms of Tolerance [PDF]
, 1995 Demetris, AJ, Starzl, TE
core +1 more source
Integrative Zoology, EarlyView.Kaempferol modulates the tryptophan metabolism pathway by increasing the abundances of Christensenellaceae R7 group, Bacteroides, and Blautia and reducing that of Rikenellaceae RC9 gut group, thereby significantly increasing the levels of ILA and IAA. This process inhibits the activation of NF‐κB/NLRP3 signaling pathway, reduces pro‐inflammatory factor
Xiangyu Liu +3 more
wiley +1 more source
Urology Journal, 2007 Introduction: Microchimerism has become a familiar term in the past few years. Many groups all over the globe, specializing in a diverse array of basic and medical sciences, have turned their attention to microchimerism, its possible role in disease ...
Mandana Mohyeddin +2 more
doaj
Allergy, EarlyView.ABSTRACT In the last decades, critical advancements in research technology and knowledge on disease mechanisms steered therapeutic approaches for chronic inflammatory diseases towards unprecedented target specificity. For allergic and chronic lung diseases, biologic drugs pioneered this goal, acquiring on the way—through the clinical use of monoclonal ...
F. Roth‐Walter +20 more
wiley +1 more source