Peripheral CD200R signaling: A critical regulator of post-stroke inflammation in aged mice. [PDF]
Ngwa C +5 more
europepmc +1 more source
ABSTRACT Objectives This study investigates the expansion of CAR T‐cells and its association to treatment outcome. Methods Patients with aggressive B‐cell lymphomas treated with anti‐CD19 CAR T‐cell therapy axicabtagene ciloleucel (axi‐cel) at Skåne and Sahlgrenska University Hospitals from 2019 to October 2024 were included.
Louise Olsson Werne +6 more
wiley +1 more source
Depletion of Sorcs3 Activates Totipotency in Mouse Embryonic Stem Cells by Modulating Key Signaling Pathways. [PDF]
Zhang W +12 more
europepmc +1 more source
Successful hamster-to-rat liver xenotransplantation under fk506 immunosuppression induces unresponsiveness to hamster heart and skin [PDF]
Celli, S +5 more
core
ABSTRACT Adult T‐cell leukemia/lymphoma (ATL) is an aggressive hematological malignancy with a poor prognosis and limited therapeutic options. ATL cells exhibit aberrant surface glycosylation patterns resulting from dysregulated glycosyltransferase expression, representing a potentially tumor‐specific therapeutic target.
Yuichiro Uchida +7 more
wiley +1 more source
African pygmy mouse iPSCs as a model for in vitro embryogenesis, interspecies chimerism, and blastocyst complementation. [PDF]
Gjonlleshaj P +9 more
europepmc +1 more source
Retreatment with talquetamab and pomalidomide in triple‐class–BCMA–GPRC5D refractory myeloma
British Journal of Haematology, EarlyView.
Kian J. Rahbari +4 more
wiley +1 more source
Clinical impact of early microchimerism dynamics after transplantation with enhanced dual-conditioning regimen in hematological diseases. [PDF]
Gu Y, Du S, Yang Y, Ding J.
europepmc +1 more source
Tissue Resident Memory Cells: Friend or Foe?
Tissue‐resident memory T cells (TRM cells) are specialised immune cells in barrier tissues like the lungs, skin and gut, providing rapid host defence and tumour surveillance. Their retention and differentiation are regulated by molecules such as CD69, CD103 and TGF‐β. Dysregulation of TRM cells can lead to chronic activation, driving conditions such as
Chidimma F. Chude +2 more
wiley +1 more source

