Results 41 to 50 of about 685,742 (313)

Efficacy of BEAM versus BeEAM conditioning regimens in autologous hematopoietic stem cell transplantation for diffuse large B-cell lymphoma: a retrospective single-center study

Frontiers in Oncology
The BEAM regimen (carmustine, etoposide, cytarabine, melphalan) is the standard conditioning regimen for autologous hematopoietic stem cell transplantation (auto-HSCT) in diffuse large B-cell lymphoma (DLBCL).
Saibiya Akebaer, Gang Chen, Jianli Xu, Kaile Zhang, Ruixue Yang, Chunxia Han, Jia Hou, Ming Jiang, Hailong Yuan   +8 more
doaj   +1 more source

Dose intensity for conditioning in allogeneic hematopoietic cell transplantation: can we recommend “when and for whom” in 2021?

Haematologica, 2021
Allogeneic hematopoietic stem-cell transplantation is a potentially curative therapy for various hematologic diseases. An essential component of this procedure is the pre-transplant conditioning regimen, which should facilitate engraftment and reduce or
Nico Gagelmann, Nicolaus Kröger
doaj   +1 more source

Dynamics of circulating dendritic cells and cytokines after kidney transplantation—No effect of remote ischaemic conditioning [PDF]

, 2021
Inflammation resulting from ischaemia/reperfusion injury can cause kidney graft dysfunction, increase the risk of delayed graft function and possibly reduce long‐term graft survival. Remote ischaemic conditioning may protect against ischaemia/reperfusion
Svendsen, Morten Bue, Bue Svendsen, Morten, Eijken, Marco, Oltean, Mihai, Ravlo, Kristian, Møller, Bjarne K, Steen Petersen, Mikkel, Krogstrup, Nicoline V., Jespersen, Bente, Birn, Henrik, Krogstrup, Nicoline V, Nielsen, Marie B., Møller, Bjarne K., Abdel‐Halim, Chadi, Abdel-Halim, Chadi, Petersen, Mikkel Steen, Nielsen, Marie B   +16 more
core   +1 more source

Comparative Drug Response Profiling in Neuroblastoma Cell Lines and Patient‐Derived Tumor Organoids

Pediatric Blood &Cancer, EarlyView.
ABSTRACT High‐risk neuroblastoma remains a leading cause of pediatric cancer mortality, and improved preclinical models are needed to guide therapeutic developments. We screened seven high‐risk neuroblastoma cell lines and three patient‐derived tumor organoids with 528 compounds alongside bone marrow controls, and compared them with external datasets ...
Krzysztof Wierbiłowicz, Se Whee Sammy Park, Aironas Los, Ernest Liu, Nona Struyf, Tom Erkers, Sören Lehmann, Jan J. Molenaar, Jakob Stenman, Olli Kallioniemi, Päivi Östling, Brinton Seashore‐Ludlow, Kasper Karlsson   +12 more
wiley   +1 more source

Post-transplantation Cyclophosphamide and Sirolimus after Haploidentical Hematopoietic Stem Cell Transplantation Using a Treosulfan-based Myeloablative Conditioning and Peripheral Blood Stem Cells

, 2015
Haploidentical hematopoietic stem cell transplantation (HSCT) performed using bone marrow (BM) grafts and post-transplantation cyclophosphamide (PTCy) has gained much interest for the excellent toxicity profile after both reduced-intensity and ...
Milani R, Crucitti L, Lupo Stanghellini MT, Bellio L, Peccatori J., BONINI , MARIA CHIARA, Carrabba MG, De Freitas T, Corti C, Cieri N, Levati G, Marktel S, Vago L, Greco R, Assanelli A, Giglio F, Lorentino F, Morelli M, Bernardi M, CICERI , FABIO   +19 more
core   +2 more sources

State-of-the-art review: allogeneic stem cell transplantation for myelofibrosis in 2019

Haematologica, 2019
Advances in understanding the pathogenesis and molecular landscape of myelofibrosis have occurred over the last decade. Treating physicians now have access to an ever-evolving armamentarium of novel agents to treat patients, although allogeneic ...
Donal P. McLornan, Ibrahim Yakoub-Agha, Marie Robin, Yves Chalandon, Claire N. Harrison, Nicolaus Kroger   +5 more
doaj   +1 more source

Posttransplantation Lymphoproliferative Disease Treated by Retransplantation

Case Reports in Immunology, 2020
Epstein–Barr virus- (EBV-) induced posttransplantation lymphoproliferative disease (PTLD) is a life-threatening complication following allogeneic stem cell transplantation. The main risk factor is anti-thymocyte globulin (ATG).
Ingerid Weum Abrahamsen, Bjørn Christer Grønvold, Else Marit Inderberg, Nadia Mensali, Jonas Mattsson, Tobias Gedde-Dahl   +5 more
doaj   +1 more source

A case report: high dose melphalan as a conditioning regimen for multiple myeloma induces sinus arrest

Cardio-Oncology, 2020
High dose melphalan is commonly used as a conditioning regimen for autologous stem cell transplantation in multiple myeloma. There are reports of adverse cardiac events with melphalan manifested by supraventricular tachycardia and atrial fibrillation ...
Liang-Liang Ma, Ying Liu, Si-Xun Jia, Hai-Chen Lv, Mei-Yun Fang, Yun-Long Xia   +5 more
doaj   +1 more source

Impact of Hyperferritinemia on the Outcome of Reduced-Intensity Conditioning Allogeneic Hematopoietic Cell Transplantation for Lymphoid Malignancies [PDF]

, 2013
Hyperferritinemia has been associated with adverse outcomes after allogeneic hematopoietic cell transplantation (allo-HCT) with myeloablative conditioning. However, its characteristics and impact on the outcome in the reduced-intensity conditioning (RIC)
Martino Bofarull, Rodrigo, Sierra, Jorge, López-Anglada, Lucía, Pérez-Simón, José Antonio, Universitat Autònoma de Barcelona. Departament de Medicina, Fernandez Aviles, Francesc, Carreras, Enric, Valcárcel, David, Novelli, Silvana, Piñana, José Luis, Barba, Pere, Rovira Argelagués, Montserrat, García Cadenas, Irene, López Corral, Lucia   +13 more
core   +1 more source

Retrospective Analysis of Donor Lymphocyte Infusions in Pediatric Patients With Mixed Chimerism After Hematopoietic Stem Cell Transplantation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Allogeneic hematopoietic stem cell transplantation (alloHSCT) is an essential therapy for several malignant and nonmalignant diseases, but relapse and graft loss remain the principal threats to its success. Routine monitoring of chimerism and minimal residual disease (MRD) enables early detection of imminent recurrence and guides ...
Carmen Junk, Sebastian Michaelis, Michaela Döring, Thomas Eichholz, Ursula Holzer, Martin Ebinger, Tim Flaadt, Rupert Handgretinger, Peter Lang, Jan Frederic Weller, Markus Mezger   +10 more
wiley   +1 more source